The effectiveness of adjunct mindfulness-based intervention in treatment of bipolar disorder: A systematic review and meta-analysis.

<h4>Background</h4> <p>Mindfulness-based interventions (MBIs) have been increasingly used as an adjunctive treatment to pharmacotherapy for a few psychiatric disorders. However, few studies have investigated the efficacy of MBIs in bipolar disorder (BD).</p> <h4>Method...

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Egile Nagusiak: Chu, C, Stubbs, B, Chen, T, Tang, C, Li, D, Yang, W, Wu, C, Carvalho, A, Vieta, E, Miklowitz, D, Tseng, P, Lin, P
Formatua: Journal article
Hizkuntza:English
Argitaratua: Elsevier 2017
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author Chu, C
Stubbs, B
Chen, T
Tang, C
Li, D
Yang, W
Wu, C
Carvalho, A
Vieta, E
Miklowitz, D
Tseng, P
Lin, P
author_facet Chu, C
Stubbs, B
Chen, T
Tang, C
Li, D
Yang, W
Wu, C
Carvalho, A
Vieta, E
Miklowitz, D
Tseng, P
Lin, P
author_sort Chu, C
collection OXFORD
description <h4>Background</h4> <p>Mindfulness-based interventions (MBIs) have been increasingly used as an adjunctive treatment to pharmacotherapy for a few psychiatric disorders. However, few studies have investigated the efficacy of MBIs in bipolar disorder (BD).</p> <h4>Methods</h4> <p>We performed a systematic review and meta-analysis to evaluate the efficacy of MBIs as an adjunctive treatment in BD. Major electronic databases were independently searched by two authors for controlled and uncontrolled studies which examined the effects of MBIs on psychiatric symptoms in subjects with BD. Data from original studies were synthesized by using a random effects model.</p> <h4>Results</h4> <p>Twelve trials were eligible for inclusion into current meta-analysis, including three controlled studies (n=132) and nine uncontrolled studies (n=142). In within-group analysis, MBIs significantly reduced depressive (7 studies, n=100, Hedges’ g=0.58, p&lt;0.001) and anxiety (4 studies, n=68, Hedges’ g=0.34, p=0.043) symptoms, but not manic symptoms (6 studies, n=89, Hedges’ g=0.09, p=0.488) and cognition (3 studies, n=43, Hedges’ g=0.35, p=0.171), compared to baseline. In between-group analysis (intervention group versus waiting list group, all patients with BD), MBIs did not reduce depressive (3 studies, n=132, Hedges’ g=0.46, p=0.315) or anxiety (3 studies, n=132, Hedges’ g=0.33, p=0.578) symptoms.</p> <h4>Limitations</h4> <p>Only three controlled trials compared MBIs to control conditions</p> <h4>Conclusions</h4> <p>Our meta-analysis showed significantly beneficial effects on depressive and anxiety symptoms of BD patients in within-group analysis. However, this significance was not observed in comparison with the control</p>
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spelling oxford-uuid:e5bdc5ee-3d2b-4685-9da5-fe531a8f09d62022-03-27T10:26:11ZThe effectiveness of adjunct mindfulness-based intervention in treatment of bipolar disorder: A systematic review and meta-analysis.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:e5bdc5ee-3d2b-4685-9da5-fe531a8f09d6EnglishSymplectic Elements at OxfordElsevier2017Chu, CStubbs, BChen, TTang, CLi, DYang, WWu, CCarvalho, AVieta, EMiklowitz, DTseng, PLin, P <h4>Background</h4> <p>Mindfulness-based interventions (MBIs) have been increasingly used as an adjunctive treatment to pharmacotherapy for a few psychiatric disorders. However, few studies have investigated the efficacy of MBIs in bipolar disorder (BD).</p> <h4>Methods</h4> <p>We performed a systematic review and meta-analysis to evaluate the efficacy of MBIs as an adjunctive treatment in BD. Major electronic databases were independently searched by two authors for controlled and uncontrolled studies which examined the effects of MBIs on psychiatric symptoms in subjects with BD. Data from original studies were synthesized by using a random effects model.</p> <h4>Results</h4> <p>Twelve trials were eligible for inclusion into current meta-analysis, including three controlled studies (n=132) and nine uncontrolled studies (n=142). In within-group analysis, MBIs significantly reduced depressive (7 studies, n=100, Hedges’ g=0.58, p&lt;0.001) and anxiety (4 studies, n=68, Hedges’ g=0.34, p=0.043) symptoms, but not manic symptoms (6 studies, n=89, Hedges’ g=0.09, p=0.488) and cognition (3 studies, n=43, Hedges’ g=0.35, p=0.171), compared to baseline. In between-group analysis (intervention group versus waiting list group, all patients with BD), MBIs did not reduce depressive (3 studies, n=132, Hedges’ g=0.46, p=0.315) or anxiety (3 studies, n=132, Hedges’ g=0.33, p=0.578) symptoms.</p> <h4>Limitations</h4> <p>Only three controlled trials compared MBIs to control conditions</p> <h4>Conclusions</h4> <p>Our meta-analysis showed significantly beneficial effects on depressive and anxiety symptoms of BD patients in within-group analysis. However, this significance was not observed in comparison with the control</p>
spellingShingle Chu, C
Stubbs, B
Chen, T
Tang, C
Li, D
Yang, W
Wu, C
Carvalho, A
Vieta, E
Miklowitz, D
Tseng, P
Lin, P
The effectiveness of adjunct mindfulness-based intervention in treatment of bipolar disorder: A systematic review and meta-analysis.
title The effectiveness of adjunct mindfulness-based intervention in treatment of bipolar disorder: A systematic review and meta-analysis.
title_full The effectiveness of adjunct mindfulness-based intervention in treatment of bipolar disorder: A systematic review and meta-analysis.
title_fullStr The effectiveness of adjunct mindfulness-based intervention in treatment of bipolar disorder: A systematic review and meta-analysis.
title_full_unstemmed The effectiveness of adjunct mindfulness-based intervention in treatment of bipolar disorder: A systematic review and meta-analysis.
title_short The effectiveness of adjunct mindfulness-based intervention in treatment of bipolar disorder: A systematic review and meta-analysis.
title_sort effectiveness of adjunct mindfulness based intervention in treatment of bipolar disorder a systematic review and meta analysis
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