The effectiveness of adjunct mindfulness-based intervention in treatment of bipolar disorder: A systematic review and meta-analysis.
<h4>Background</h4> <p>Mindfulness-based interventions (MBIs) have been increasingly used as an adjunctive treatment to pharmacotherapy for a few psychiatric disorders. However, few studies have investigated the efficacy of MBIs in bipolar disorder (BD).</p> <h4>Method...
| Prif Awduron: | , , , , , , , , , , , |
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| Fformat: | Journal article |
| Iaith: | English |
| Cyhoeddwyd: |
Elsevier
2017
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| _version_ | 1826302044991913984 |
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| author | Chu, C Stubbs, B Chen, T Tang, C Li, D Yang, W Wu, C Carvalho, A Vieta, E Miklowitz, D Tseng, P Lin, P |
| author_facet | Chu, C Stubbs, B Chen, T Tang, C Li, D Yang, W Wu, C Carvalho, A Vieta, E Miklowitz, D Tseng, P Lin, P |
| author_sort | Chu, C |
| collection | OXFORD |
| description | <h4>Background</h4> <p>Mindfulness-based interventions (MBIs) have been increasingly used as an adjunctive treatment to pharmacotherapy for a few psychiatric disorders. However, few studies have investigated the efficacy of MBIs in bipolar disorder (BD).</p> <h4>Methods</h4> <p>We performed a systematic review and meta-analysis to evaluate the efficacy of MBIs as an adjunctive treatment in BD. Major electronic databases were independently searched by two authors for controlled and uncontrolled studies which examined the effects of MBIs on psychiatric symptoms in subjects with BD. Data from original studies were synthesized by using a random effects model.</p> <h4>Results</h4> <p>Twelve trials were eligible for inclusion into current meta-analysis, including three controlled studies (n=132) and nine uncontrolled studies (n=142). In within-group analysis, MBIs significantly reduced depressive (7 studies, n=100, Hedges’ g=0.58, p<0.001) and anxiety (4 studies, n=68, Hedges’ g=0.34, p=0.043) symptoms, but not manic symptoms (6 studies, n=89, Hedges’ g=0.09, p=0.488) and cognition (3 studies, n=43, Hedges’ g=0.35, p=0.171), compared to baseline. In between-group analysis (intervention group versus waiting list group, all patients with BD), MBIs did not reduce depressive (3 studies, n=132, Hedges’ g=0.46, p=0.315) or anxiety (3 studies, n=132, Hedges’ g=0.33, p=0.578) symptoms.</p> <h4>Limitations</h4> <p>Only three controlled trials compared MBIs to control conditions</p> <h4>Conclusions</h4> <p>Our meta-analysis showed significantly beneficial effects on depressive and anxiety symptoms of BD patients in within-group analysis. However, this significance was not observed in comparison with the control</p> |
| first_indexed | 2024-03-07T05:41:33Z |
| format | Journal article |
| id | oxford-uuid:e5bdc5ee-3d2b-4685-9da5-fe531a8f09d6 |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-07T05:41:33Z |
| publishDate | 2017 |
| publisher | Elsevier |
| record_format | dspace |
| spelling | oxford-uuid:e5bdc5ee-3d2b-4685-9da5-fe531a8f09d62022-03-27T10:26:11ZThe effectiveness of adjunct mindfulness-based intervention in treatment of bipolar disorder: A systematic review and meta-analysis.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:e5bdc5ee-3d2b-4685-9da5-fe531a8f09d6EnglishSymplectic Elements at OxfordElsevier2017Chu, CStubbs, BChen, TTang, CLi, DYang, WWu, CCarvalho, AVieta, EMiklowitz, DTseng, PLin, P <h4>Background</h4> <p>Mindfulness-based interventions (MBIs) have been increasingly used as an adjunctive treatment to pharmacotherapy for a few psychiatric disorders. However, few studies have investigated the efficacy of MBIs in bipolar disorder (BD).</p> <h4>Methods</h4> <p>We performed a systematic review and meta-analysis to evaluate the efficacy of MBIs as an adjunctive treatment in BD. Major electronic databases were independently searched by two authors for controlled and uncontrolled studies which examined the effects of MBIs on psychiatric symptoms in subjects with BD. Data from original studies were synthesized by using a random effects model.</p> <h4>Results</h4> <p>Twelve trials were eligible for inclusion into current meta-analysis, including three controlled studies (n=132) and nine uncontrolled studies (n=142). In within-group analysis, MBIs significantly reduced depressive (7 studies, n=100, Hedges’ g=0.58, p<0.001) and anxiety (4 studies, n=68, Hedges’ g=0.34, p=0.043) symptoms, but not manic symptoms (6 studies, n=89, Hedges’ g=0.09, p=0.488) and cognition (3 studies, n=43, Hedges’ g=0.35, p=0.171), compared to baseline. In between-group analysis (intervention group versus waiting list group, all patients with BD), MBIs did not reduce depressive (3 studies, n=132, Hedges’ g=0.46, p=0.315) or anxiety (3 studies, n=132, Hedges’ g=0.33, p=0.578) symptoms.</p> <h4>Limitations</h4> <p>Only three controlled trials compared MBIs to control conditions</p> <h4>Conclusions</h4> <p>Our meta-analysis showed significantly beneficial effects on depressive and anxiety symptoms of BD patients in within-group analysis. However, this significance was not observed in comparison with the control</p> |
| spellingShingle | Chu, C Stubbs, B Chen, T Tang, C Li, D Yang, W Wu, C Carvalho, A Vieta, E Miklowitz, D Tseng, P Lin, P The effectiveness of adjunct mindfulness-based intervention in treatment of bipolar disorder: A systematic review and meta-analysis. |
| title | The effectiveness of adjunct mindfulness-based intervention in treatment of bipolar disorder: A systematic review and meta-analysis. |
| title_full | The effectiveness of adjunct mindfulness-based intervention in treatment of bipolar disorder: A systematic review and meta-analysis. |
| title_fullStr | The effectiveness of adjunct mindfulness-based intervention in treatment of bipolar disorder: A systematic review and meta-analysis. |
| title_full_unstemmed | The effectiveness of adjunct mindfulness-based intervention in treatment of bipolar disorder: A systematic review and meta-analysis. |
| title_short | The effectiveness of adjunct mindfulness-based intervention in treatment of bipolar disorder: A systematic review and meta-analysis. |
| title_sort | effectiveness of adjunct mindfulness based intervention in treatment of bipolar disorder a systematic review and meta analysis |
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