Genomic risk prediction of coronary artery disease in 480,000 adults: implications for primary prevention

Genomic risk prediction of coronary artery disease in 480,000 adults: implications for primary prevention

<strong>Background</strong> Coronary artery disease (CAD) has substantial heritability and a polygenic architecture. However, the potential of genomic risk scores to help predict CAD outcomes has not been evaluated comprehensively, because available studies have involved limited genomic...

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Bibliografiska uppgifter
Huvudupphovsmän: Inouye, M, Abraham, G, Nelson, C, Wood, A, Sweeting, M, Dudbridge, F, Lai, F, Kaptoge, S, Brozynska, M, Wang, T, Ye, S, Webb, T, Rutter, M, Tzoulaki, I, Patel, R, Loos, R, Keavney, B, Hemingway, H, Thompson, J, Watkins, H, Deloukas, P, Di Angelantonio, E, Butterworth, A, Danesh, J, Samani, N, UK Biobank CardioMetabolic Consortium CHD Working Group
Materialtyp: Journal article
Språk:English
Publicerad: Elsevier 2018

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