Sustained dysfunction of antiviral CD8+ T lymphocytes after infection with hepatitis C virus.

Hepatitis C virus (HCV) sets up persistent infection in the majority of those exposed. It is likely that, as with other persistent viral infections, the efficacy of T-lymphocyte responses influences long-term outcome. However, little is known about the functional capacity of HCV-specific T-lymphocyt...

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Bibliographic Details
Main Authors: Gruener, N, Lechner, F, Jung, M, Diepolder, H, Gerlach, T, Lauer, G, Walker, B, Sullivan, J, Phillips, R, Pape, G, Klenerman, P
Format: Journal article
Language:English
Published: 2001