Sustained dysfunction of antiviral CD8+ T lymphocytes after infection with hepatitis C virus.

Sustained dysfunction of antiviral CD8+ T lymphocytes after infection with hepatitis C virus.

Hepatitis C virus (HCV) sets up persistent infection in the majority of those exposed. It is likely that, as with other persistent viral infections, the efficacy of T-lymphocyte responses influences long-term outcome. However, little is known about the functional capacity of HCV-specific T-lymphocyt...

Podrobná bibliografie
Hlavní autoři:	Gruener, N, Lechner, F, Jung, M, Diepolder, H, Gerlach, T, Lauer, G, Walker, B, Sullivan, J, Phillips, R, Pape, G, Klenerman, P
Médium:	Journal article
Jazyk:	English
Vydáno:	2001

Podobné jednotky

Immune response in acute hepatitis C: Enumeration of virus specific CD8+T cells with ELISPOT assay and tetramers
Autor: Gruener, N, a další
Vydáno: (1999)

Detection of HCV-specific CD8+T cells in acuter hepatitis C which are impaired in cytolytic function and production of cytokines.
Autor: Gruener, N, a další
Vydáno: (2000)

CD8+ T lymphocyte responses are induced during acute hepatitis C virus infection but are not sustained.
Autor: Lechner, F, a další
Vydáno: (2000)

Do antiviral CD8+ T cells select hepatitis C virus escape mutants? Analysis in diverse epitopes targeted by human intrahepatic CD8+ T lymphocytes.
Autor: Komatsu, H, a další
Vydáno: (2006)

Pervasive influence of hepatitis C virus on the phenotype of antiviral CD8+ T cells.
Autor: Lucas, M, a další
Vydáno: (2004)

Studies of human antiviral CD8+ lymphocytes using class I peptide tetramers.
Autor: Lechner, F, a další
Vydáno: (2001)

Exhaustion of virus specific CD4+T cells during acute hepatitis C
Autor: Ulsenheimer, A, a další
Vydáno: (2007)

Transient immunological control during acute hepatitis C virus infection: ex vivo analysis of helper T-cell responses.
Autor: Ulsenheimer, A, a další
Vydáno: (2006)

CD4+CD25+T-regulatory lymphocytes control expansion of hepatitis virus specific CD8+T cells.
Autor: Rushbrook, S, a další
Vydáno: (2003)

Ex vivo analysis of phenotype and TCR usage in relation to CD45 isoform expression on cytomegalovirus-specific CD8+ T lymphocytes.
Autor: Vargas, A, a další
Vydáno: (2001)

Direct quantitation of rapid elimination of viral antigen-positive lymphocytes by antiviral CD8(+) T cells in vivo.
Autor: Barchet, W, a další
Vydáno: (2000)

Cytotoxic T lymphocytes, chemokines and antiviral immunity.
Autor: Price, D, a další
Vydáno: (1999)

CD161 expression on hepatitis C virus-specific CD8+ T cells suggests a distinct pathway of T cell differentiation.
Autor: Northfield, J, a další
Vydáno: (2008)

CD8+ cytotoxic lymphocyte responses against cytomegalovirus after liver transplantation: correlation with time from transplant to receipt of tacrolimus.
Autor: Hassan-Walker, A, a další
Vydáno: (2001)

Memory inflation: continuous accumulation of antiviral CD8+ T cells over time.
Autor: Karrer, U, a další
Vydáno: (2003)

Evolution of diverse antiviral CD8+ T cell populations after murine cytomegalovirus infection.
Autor: Sierro, S, a další
Vydáno: (2005)

Comprehensive analysis of CD8(+)-T-cell responses against hepatitis C virus reveals multiple unpredicted specificities.
Autor: Lauer, G, a další
Vydáno: (2002)

Comprehensive analysis of the HCV-specific CD8+T cell response in individuals with chronic or resolved HCV infection.
Autor: Lauer, G, a další
Vydáno: (2001)

Dynamics of the CD8+and CD4+T cell immune response during acute HCV infection with spontaneous resolution.
Autor: Wong, D, a další
Vydáno: (1999)

CD8+ lymphocyte (CD8+L) responses in acute hepatitis C virus (HCV) infection
Autor: Christie, J, a další
Vydáno: (1998)

CD3+CD4+CD8+ T-LYMPHOCYTES COUNT IN PROGNOSIS OF EARLY KIDNEY ALLOGRAFT DYSFUNCTION
Autor: Zybleva S. V., a další
Vydáno: (2020-03-01)

Memory deflation: impact of CMV on antiviral CD8 T cell memory pools
Autor: Lee, L, a další
Vydáno: (2013)

CD8+ Lymphocytes from Healthy Blood Donors Secrete Antiviral Levels of Interferon-Alpha
Autor: Fernando Teque, a další
Vydáno: (2023-03-01)

Tracking virus-specific CD4+ T cells during and after acute hepatitis C virus infection.
Autor: Lucas, M, a další
Vydáno: (2007)

Novel functions, phenotype and homing of Human CD8aa cells
Autor: Walker, L, a další
Vydáno: (2010)

CD8(+) T lymphocyte (CD8(+)L) responses in acute and chronic hepatitis C virus (HCV) infection.
Autor: Christie, J, a další
Vydáno: (1998)

Antagonism of cytotoxic T-lymphocyte activation by soluble CD8.
Autor: Sewell, A, a další
Vydáno: (1999)

Memory CD8+ T cells vary in differentiation phenotype in different persistent virus infections.
Autor: Appay, V, a další
Vydáno: (2002)

T cell failure in hepatitis C virus infection.
Autor: Barnes, E, a další
Vydáno: (2002)

Memory inflation: Continous accumulation of antiviral CD8(+) T cells over time. (vol 170, pg 2022, 2003)
Autor: Karrer, U, a další
Vydáno: (2003)

Ultra-sensitive class I tetramer analysis reveals previously undetectable populations of antiviral CD8+ T cells.
Autor: Barnes, E, a další
Vydáno: (2004)

Inflation vs. Exhaustion of Antiviral CD8+ T-Cell Populations in Persistent Infections: Two Sides of the Same Coin?
Autor: Emanuele Marchi, a další
Vydáno: (2019-03-01)

Virus-specific CD8+ T lymphocytes within the normal human liver.
Autor: Ward, S, a další
Vydáno: (2004)

CD8AA T CELLS: A NOVEL LINEAGE ENRICHED IN THE LIVER IN CHRONIC HCV
Autor: Walker, L, a další
Vydáno: (2010)

Immunosuppression for liver transplantation with tacrolimus impairs specific cytomegalovirus CD8 immune responses
Autor: Hassan-Walker, A, a další
Vydáno: (2000)

Life, activation and death of intrahepatic lymphocytes in chronic hepatitis C.
Autor: Valiante, N, a další
Vydáno: (2000)

Inflation vs exhaustion of antiviral CD8+ t-cell populations in persistent infections: two sides of the same coin?
Autor: Marchi, E, a další
Vydáno: (2019)

Underwhelming the immune response: effect of slow virus growth on CD8+-T-lymphocyte responses.
Autor: Bocharov, G, a další
Vydáno: (2004)

Underwhelming the immune response: Effect of slow virus growth on CD(8+) T-lymphocyte responses
Autor: Bocharov, G, a další
Vydáno: (2004)

Longitudinal analysis of CD8 T-cell responses to HIV and hepatitis C virus in a cohort of co-infected haemophiliacs.
Autor: Harcourt, G, a další
Vydáno: (2005)