Sustained dysfunction of antiviral CD8+ T lymphocytes after infection with hepatitis C virus.

Sustained dysfunction of antiviral CD8+ T lymphocytes after infection with hepatitis C virus.

Hepatitis C virus (HCV) sets up persistent infection in the majority of those exposed. It is likely that, as with other persistent viral infections, the efficacy of T-lymphocyte responses influences long-term outcome. However, little is known about the functional capacity of HCV-specific T-lymphocyt...

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Manylion Llyfryddiaeth
Prif Awduron:	Gruener, N, Lechner, F, Jung, M, Diepolder, H, Gerlach, T, Lauer, G, Walker, B, Sullivan, J, Phillips, R, Pape, G, Klenerman, P
Fformat:	Journal article
Iaith:	English
Cyhoeddwyd:	2001

Eitemau Tebyg

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gan: Komatsu, H, et al.
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gan: Lucas, M, et al.
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Studies of human antiviral CD8+ lymphocytes using class I peptide tetramers.
gan: Lechner, F, et al.
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gan: Ulsenheimer, A, et al.
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Transient immunological control during acute hepatitis C virus infection: ex vivo analysis of helper T-cell responses.
gan: Ulsenheimer, A, et al.
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gan: Rushbrook, S, et al.
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Ex vivo analysis of phenotype and TCR usage in relation to CD45 isoform expression on cytomegalovirus-specific CD8+ T lymphocytes.
gan: Vargas, A, et al.
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gan: Barchet, W, et al.
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gan: Price, D, et al.
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gan: Northfield, J, et al.
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CD8+ cytotoxic lymphocyte responses against cytomegalovirus after liver transplantation: correlation with time from transplant to receipt of tacrolimus.
gan: Hassan-Walker, A, et al.
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gan: Karrer, U, et al.
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Evolution of diverse antiviral CD8+ T cell populations after murine cytomegalovirus infection.
gan: Sierro, S, et al.
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Comprehensive analysis of CD8(+)-T-cell responses against hepatitis C virus reveals multiple unpredicted specificities.
gan: Lauer, G, et al.
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Comprehensive analysis of the HCV-specific CD8+T cell response in individuals with chronic or resolved HCV infection.
gan: Lauer, G, et al.
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Dynamics of the CD8+and CD4+T cell immune response during acute HCV infection with spontaneous resolution.
gan: Wong, D, et al.
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CD8+ lymphocyte (CD8+L) responses in acute hepatitis C virus (HCV) infection
gan: Christie, J, et al.
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Tracking virus-specific CD4+ T cells during and after acute hepatitis C virus infection.
gan: Lucas, M, et al.
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Novel functions, phenotype and homing of Human CD8aa cells
gan: Walker, L, et al.
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CD8(+) T lymphocyte (CD8(+)L) responses in acute and chronic hepatitis C virus (HCV) infection.
gan: Christie, J, et al.
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Antagonism of cytotoxic T-lymphocyte activation by soluble CD8.
gan: Sewell, A, et al.
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Memory CD8+ T cells vary in differentiation phenotype in different persistent virus infections.
gan: Appay, V, et al.
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T cell failure in hepatitis C virus infection.
gan: Barnes, E, et al.
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Memory inflation: Continous accumulation of antiviral CD8(+) T cells over time. (vol 170, pg 2022, 2003)
gan: Karrer, U, et al.
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Ultra-sensitive class I tetramer analysis reveals previously undetectable populations of antiviral CD8+ T cells.
gan: Barnes, E, et al.
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Virus-specific CD8+ T lymphocytes within the normal human liver.
gan: Ward, S, et al.
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gan: Hassan-Walker, A, et al.
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Life, activation and death of intrahepatic lymphocytes in chronic hepatitis C.
gan: Valiante, N, et al.
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gan: Marchi, E, et al.
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Underwhelming the immune response: effect of slow virus growth on CD8+-T-lymphocyte responses.
gan: Bocharov, G, et al.
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Underwhelming the immune response: Effect of slow virus growth on CD(8+) T-lymphocyte responses
gan: Bocharov, G, et al.
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Longitudinal analysis of CD8 T-cell responses to HIV and hepatitis C virus in a cohort of co-infected haemophiliacs.
gan: Harcourt, G, et al.
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