Sustained dysfunction of antiviral CD8+ T lymphocytes after infection with hepatitis C virus.
Hepatitis C virus (HCV) sets up persistent infection in the majority of those exposed. It is likely that, as with other persistent viral infections, the efficacy of T-lymphocyte responses influences long-term outcome. However, little is known about the functional capacity of HCV-specific T-lymphocyt...
Main Authors: | Gruener, N, Lechner, F, Jung, M, Diepolder, H, Gerlach, T, Lauer, G, Walker, B, Sullivan, J, Phillips, R, Pape, G, Klenerman, P |
---|---|
格式: | Journal article |
语言: | English |
出版: |
2001
|
相似书籍
-
Immune response in acute hepatitis C: Enumeration of virus specific CD8+T cells with ELISPOT assay and tetramers
由: Gruener, N, et al.
出版: (1999) -
Detection of HCV-specific CD8+T cells in acuter hepatitis C which are impaired in cytolytic function and production of cytokines.
由: Gruener, N, et al.
出版: (2000) -
CD8+ T lymphocyte responses are induced during acute hepatitis C virus infection but are not sustained.
由: Lechner, F, et al.
出版: (2000) -
Do antiviral CD8+ T cells select hepatitis C virus escape mutants? Analysis in diverse epitopes targeted by human intrahepatic CD8+ T lymphocytes.
由: Komatsu, H, et al.
出版: (2006) -
Pervasive influence of hepatitis C virus on the phenotype of antiviral CD8+ T cells.
由: Lucas, M, et al.
出版: (2004)