IκB kinase 2 but not NF-κB-inducing kinase is essential for effective DC antigen presentation in the allogeneic mixed lymphocyte reaction

IκB kinase 2 but not NF-κB-inducing kinase is essential for effective DC antigen presentation in the allogeneic mixed lymphocyte reaction

Although dendritic cells (DCs) are the most potent antigen-presenting cells involved in numerous physiologic and pathologic processes, little is known about the signaling pathways that regulate DC activation and antigen-presenting function. Recently, we demonstrated that nuclear factor (NF)-κB activ...

Ամբողջական նկարագրություն

Մատենագիտական մանրամասներ
Հիմնական հեղինակներ:	Andreakos, E, Smith, C, Monaco, C, Brennan, F, Foxwell, B, Feldmann, M
Ձևաչափ:	Journal article
Լեզու:	English
Հրապարակվել է:	2003

Նմանատիպ նյութեր

Ikappa B kinase 2 but not NF-kappa B-inducing kinase is essential for effective DC antigen presentation in the allogeneic mixed lymphocyte reaction.
‌: Andreakos, E, և այլն
Հրապարակվել է: (2003)

NF-κB-inducing kinase is dispensable for activation of NF-κB in inflammatory settings but essential for lymphotoxin β receptor activation of NF-κB in primary human fibroblasts
‌: Smith, C, և այլն
Հրապարակվել է: (2001)

NF-kappaB-inducing kinase is dispensable for activation of NF-kappaB in inflammatory settings but essential for lymphotoxin beta receptor activation of NF-kappaB in primary human fibroblasts.
‌: Smith, C, և այլն
Հրապարակվել է: (2001)

VEGF expression in human macrophages is NF-kappaB-dependent: studies using adenoviruses expressing the endogenous NF-kappaB inhibitor IkappaBalpha and a kinase-defective form of the IkappaB kinase 2.
‌: Kiriakidis, S, և այլն
Հրապարակվել է: (2003)

VEGF expression in human macrophages is NF-kappaB-dependent: studies using adenoviruses expressing the endogenous NF-kappaB inhibitor IkappaBalpha and a kinase-defective form of the IkappaB kinase 2.
‌: Kiriakidis, S, և այլն
Հրապարակվել է: (2003)

Activation of NF-kappaB by the intracellular expression of NF-kappaB-inducing kinase acts as a powerful vaccine adjuvant.
‌: Andreakos, E, և այլն
Հրապարակվել է: (2006)

TNFα-induced macrophage chemokine secretion is more dependent on NF-κB expression than lipopolysaccharides-induced macrophage chemokine secretion
‌: Ciesielski, C, և այլն
Հրապարակվել է: (2002)

Inhibitory-κB Kinase (IKK) α and Nuclear Factor-κB (NFκB)-Inducing Kinase (NIK) as Anti-Cancer Drug Targets
‌: Andrew Paul, և այլն
Հրապարակվել է: (2018-10-01)

Beyond NF-κB activation: nuclear functions of IκB kinase α
‌: Huang Wei-Chien, և այլն
Հրապարակվել է: (2013-01-01)

Hepatic NF‐κB‐Inducing Kinase and Inhibitor of NF‐κB Kinase Subunit α Promote Liver Oxidative Stress, Ferroptosis, and Liver Injury
‌: Xiao Zhong, և այլն
Հրապարակվել է: (2021-10-01)

Regulation of IκBα expression involves both NF-κB and the MAP kinase signaling pathways
‌: Sambucetti Lidia C, և այլն
Հրապարակվել է: (2005-10-01)

Peripheral NF-κB dysregulation in people with schizophrenia drives inflammation: putative anti-inflammatory functions of NF-κB kinases
‌: Caitlin E. Murphy, և այլն
Հրապարակվել է: (2022-01-01)

NF-κB Inducing Kinase Regulates Intestinal Immunity and Homeostasis
‌: Bingran Wang, և այլն
Հրապարակվել է: (2022-06-01)

I-κB kinase-ε deficiency improves doxorubicin-induced dilated cardiomyopathy by inhibiting the NF-κB pathway
‌: Yafeng Liu, և այլն
Հրապարակվել է: (2022-08-01)

NF-κB inducing kinase, a central signaling component of the non-canonical pathway of NF-κB, contributes to ovarian cancer progression.
‌: Masaya Uno, և այլն
Հրապարակվել է: (2014-01-01)

Noncanonical NF-κB signaling and the essential kinase NIK modulate crucial features associated with eosinophilic esophagitis pathogenesis
‌: Kristin Eden, և այլն
Հրապարակվել է: (2017-12-01)

NF-κB inducing kinase is a therapeutic target for systemic lupus erythematosus
‌: Hans D. Brightbill, և այլն
Հրապարակվել է: (2018-01-01)

Heterogeneous requirement of IkappaB kinase 2 for inflammatory cytokine and matrix metalloproteinase production in rheumatoid arthritis: implications for therapy.
‌: Andreakos, E, և այլն
Հրապարակվել է: (2003)

The NFκB-inducing kinase is essential for the developmental programming of skin-resident and IL-17-producing γδ T cells
‌: Florian Mair, և այլն
Հրապարակվել է: (2015-12-01)

PEDV ORF3 Independently Regulates IκB Kinase β-Mediated NF-κB and IFN-β Promoter Activities
‌: Challika Kaewborisuth, և այլն
Հրապարակվել է: (2020-05-01)

NF-κB as a Target for Modulating Inflammatory Responses.
‌: Gasparini, C, և այլն
Հրապարակվել է: (2012)

NF-κB as a target for modulating inflammatory responses.
‌: Gasparini, C, և այլն
Հրապարակվել է: (2012)

The rate of NF-κB nuclear translocation is regulated by PKA and A kinase interacting protein 1.
‌: Charles C King, և այլն
Հրապարակվել է: (2011-04-01)

NF-κB-Inducing Kinase Is Essential for Effective c-Rel Transactivation and Binding to the <i>Il12b</i> Promoter in Macrophages
‌: Natalia Cuesta, և այլն
Հրապարակվել է: (2025-01-01)

Functional interplay between NF-κB-inducing kinase and c-Abl kinases limits response to Aurora inhibitors in multiple myeloma
‌: Laura Mazzera, և այլն
Հրապարակվել է: (2019-12-01)

Torilin Inhibits Inflammation by Limiting TAK1-Mediated MAP Kinase and NF-κB Activation
‌: Mehari Endale, և այլն
Հրապարակվել է: (2017-01-01)

β-Myrcene Mitigates Colon Inflammation by Inhibiting MAP Kinase and NF-κB Signaling Pathways
‌: Saeeda Almarzooqi, և այլն
Հրապարակվել է: (2022-12-01)

NF-κB Members Left Home: NF-κB-Independent Roles in Cancer
‌: Carlota Colomer, և այլն
Հրապարակվել է: (2017-05-01)

MALT1 auto-proteolysis is essential for NF-κB-dependent gene transcription in activated lymphocytes.
‌: Mathijs Baens, և այլն
Հրապարակվել է: (2014-01-01)

NF-κB fingerprinting reveals heterogeneous NF-κB composition in diffuse large B-cell lymphoma
‌: Eleanor Jayawant, և այլն
Հրապարակվել է: (2023-06-01)

IκB Kinase ε Is an NFATc1 Kinase that Inhibits T Cell Immune Response
‌: Junjie Zhang, և այլն
Հրապարակվել է: (2016-07-01)

Stabilization of NF-κB-Inducing Kinase Suppresses MLL-AF9-Induced Acute Myeloid Leukemia
‌: Yan Xiu, և այլն
Հրապարակվել է: (2018-01-01)

NF-κB-inducing kinase (NIK) is activated in pancreatic β-cells but does not contribute to the development of diabetes
‌: Peng Xiao, և այլն
Հրապարակվել է: (2022-05-01)

Expression of ICAM-1, TNF-α, NFκB, and MAP kinase in tubers of the tuberous sclerosis complex
‌: Michelle Maldonado, B.S., և այլն
Հրապարակվել է: (2003-11-01)

NF-κB as the main node of resistance to receptor tyrosine kinase inhibitors in triple-negative breast cancer
‌: Behrad Darvishi, և այլն
Հրապարակվել է: (2017-06-01)

Mitogen-activated protein kinases and NFκB are involved in SP-A-enhanced responses of macrophages to mycobacteria
‌: Vigerust David J, և այլն
Հրապարակվել է: (2009-07-01)

Basal shuttle of NF-κB/IκBα in resting T lymphocytes regulates HIV-1 LTR dependent expression
‌: Mittelbrunn Maria, և այլն
Հրապարակվել է: (2007-08-01)

Inhibition of Bruton's tyrosine kinase regulates macrophage NF-κB and NLRP3 inflammasome activation in metabolic inflammation
‌: Purvis, GSD, և այլն
Հրապարակվել է: (2020)

Hypoxia Induced NF-κB
‌: Laura D’Ignazio, և այլն
Հրապարակվել է: (2016-03-01)

NF-κB in Hematological Malignancies
‌: Véronique Imbert, և այլն
Հրապարակվել է: (2017-05-01)