Synthesis of 2,4,6-trisubstituted pyridines via an olefin cross-metathesis/Heck-cyclisation-elimination sequence.
Heck reactions were performed on α,β-unsaturated-δ-sulfonamido intermediates, derived from cross metathesis, to allow the instalment of substituents at the β position. Subsequent one-pot cyclisation/elimination provides an operationally simple, catalytic and convergent synthesis of 2,4,6-trisubstitu...
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Detalles Bibliográficos
| Autores principales: |
Donohoe, T,
Bower, J,
Baker, D,
Basutto, J,
Chan, L,
Gallagher, P |
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| Formato: | Journal article
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| Lenguaje: | English |
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| Publicado: |
Royal Society of Chemistry
2011
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| Materias: | |
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