Synthesis of 2,4,6-trisubstituted pyridines via an olefin cross-metathesis/Heck-cyclisation-elimination sequence.

Synthesis of 2,4,6-trisubstituted pyridines via an olefin cross-metathesis/Heck-cyclisation-elimination sequence.

Heck reactions were performed on α,β-unsaturated-δ-sulfonamido intermediates, derived from cross metathesis, to allow the instalment of substituents at the β position. Subsequent one-pot cyclisation/elimination provides an operationally simple, catalytic and convergent synthesis of 2,4,6-trisubstitu...

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Dettagli Bibliografici
Autori principali:	Donohoe, T, Bower, J, Baker, D, Basutto, J, Chan, L, Gallagher, P
Natura:	Journal article
Lingua:	English
Pubblicazione:	Royal Society of Chemistry 2011
Soggetti:	Organic Chemistry Chemistry and Allied Sciences

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