Kinetics of reduction of tyrosine phenoxyl radicals by glutathione.

Modification of tyrosine (TyrOH) is used as a marker of oxidative and nitrosative stress. 3,3'-Dityrosine formation, in particular, reflects oxidative damage and results from the combination of two tyrosyl phenoxyl radicals (TyrO·). This reaction is in competition with reductive processes in th...

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Bibliographic Details
Main Authors: Folkes, L, Trujillo, M, Bartesaghi, S, Radi, R, Wardman, P
Format: Journal article
Language:English
Published: 2011