A new series of aryl sulfamate derivatives: design, synthesis, and biological evaluation

Steroid sulfatase (STS) has recently emerged as a drug target for management of hormone-dependent malignancies. In the present study, a new series of twenty-one aryl amido-linked sulfamate derivatives 1a-u was designed and synthesized, based upon a cyclohexyl lead compound. All members were evaluate...

Full description

Bibliographic Details
Main Authors: El-Gamal, MI, Zaraei, S-O, Foster, PA, Anbar, HS, El-Gamal, R, El-Awady, R, Potter, BVL
Format: Journal article
Language:English
Published: Elsevier 2020