A choreography of nicotinic receptors directs the dopamine neuron routine.
Modulation of the mesocorticolimbic dopamine system by nicotinic acetylcholine receptors (nAChRs) is thought to play an important role in both health and addiction. However, a clear understanding of how these receptors regulate in vivo firing activity has been elusive. In this issue of Neuron, Mamel...
| Main Authors: | , |
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| Format: | Journal article |
| Language: | English |
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2006
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| _version_ | 1797100774628524032 |
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| author | Ungless, M Cragg, S |
| author_facet | Ungless, M Cragg, S |
| author_sort | Ungless, M |
| collection | OXFORD |
| description | Modulation of the mesocorticolimbic dopamine system by nicotinic acetylcholine receptors (nAChRs) is thought to play an important role in both health and addiction. However, a clear understanding of how these receptors regulate in vivo firing activity has been elusive. In this issue of Neuron, Mameli-Engvall and colleagues report an impressive and thought-provoking series of in vivo experiments combining single-unit recordings from dopamine neurons with nAChR subunit deletions and region-specific lentiviral subunit re-expression. |
| first_indexed | 2024-03-07T05:42:23Z |
| format | Journal article |
| id | oxford-uuid:e605178e-d2ac-4928-8feb-df4ff30144f1 |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-07T05:42:23Z |
| publishDate | 2006 |
| record_format | dspace |
| spelling | oxford-uuid:e605178e-d2ac-4928-8feb-df4ff30144f12022-03-27T10:28:13ZA choreography of nicotinic receptors directs the dopamine neuron routine.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:e605178e-d2ac-4928-8feb-df4ff30144f1EnglishSymplectic Elements at Oxford2006Ungless, MCragg, SModulation of the mesocorticolimbic dopamine system by nicotinic acetylcholine receptors (nAChRs) is thought to play an important role in both health and addiction. However, a clear understanding of how these receptors regulate in vivo firing activity has been elusive. In this issue of Neuron, Mameli-Engvall and colleagues report an impressive and thought-provoking series of in vivo experiments combining single-unit recordings from dopamine neurons with nAChR subunit deletions and region-specific lentiviral subunit re-expression. |
| spellingShingle | Ungless, M Cragg, S A choreography of nicotinic receptors directs the dopamine neuron routine. |
| title | A choreography of nicotinic receptors directs the dopamine neuron routine. |
| title_full | A choreography of nicotinic receptors directs the dopamine neuron routine. |
| title_fullStr | A choreography of nicotinic receptors directs the dopamine neuron routine. |
| title_full_unstemmed | A choreography of nicotinic receptors directs the dopamine neuron routine. |
| title_short | A choreography of nicotinic receptors directs the dopamine neuron routine. |
| title_sort | choreography of nicotinic receptors directs the dopamine neuron routine |
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