Endothelial GTP cyclohydrolase and tetrahydrobiopterin regulate gestational blood pressure, uteroplacental remodeling and fetal growth
Abnormal uteroplacental remodeling leads to placental hypoperfusion, causing fetal growth restriction and pregnancy-related hypertension, which are associated with endothelial dysfunction and markers of reduced vascular NO bioavailability and oxidative stress. Tetrahydrobiopterin (BH4) is a redox co...
Huvudupphovsmän: | , , , , , , , , , , , , , , , , |
---|---|
Materialtyp: | Journal article |
Språk: | English |
Publicerad: |
American Heart Association
2021
|