Development of standard clinical endpoints for use in dengue interventional trials

Development of standard clinical endpoints for use in dengue interventional trials

Dengue is a major public health problem worldwide. Although several drug candidates have been evaluated in randomized controlled trials, none has been effective and at present, early recognition of severe dengue and timely supportive care are used to reduce mortality. While the first dengue vaccine...

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Detalhes bibliográficos
Principais autores: Tomashek, K, Wills, B, See Lum, L, Thomas, L, Durbin, A, Leo, Y, De Bosch, N, Rojas, E, Hendrickx, K, Erpicum, M, Agulto, L, Jaenisch, T, Tissera, H, Suntarattiwong, P, Collers, B, Wallace, D, Schmidt, A, Precioso, A, Narvaez, F, Thomas, S, Edelman, R, Siqueira, J, Cassetti, M, Dempsey, W, Gubler, D
Formato: Journal article
Idioma:English
Publicado em: Public Library of Science 2018

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