Signalling hypoxia by HIF hydroxylases.
Analysis of oxygen sensitive pathways that regulate the hypoxia inducible factor (HIF) transcriptional system has revealed a novel role for oxygenases in signalling hypoxia. The enzymes, which catalyse hydroxylation of specific prolyl and asparaginyl residues in the regulatory HIF-alpha subunits, be...
मुख्य लेखकों: | Schofield, C, Ratcliffe, P |
---|---|
स्वरूप: | Journal article |
भाषा: | English |
प्रकाशित: |
2005
|
समान संसाधन
-
Oxygen sensing by HIF hydroxylases.
द्वारा: Schofield, C, और अन्य
प्रकाशित: (2004) -
Inhibition of hypoxia inducible factor (HIF) hydroxylases
द्वारा: Conejo-Garcia, A, और अन्य
प्रकाशित: (2005) -
Tuning the transcriptional response to hypoxia by inhibiting HIF prolyl- and asparaginyl-hydroxylases
द्वारा: Chan, M, और अन्य
प्रकाशित: (2016) -
Hypoxia, hypoxia-inducible factors (HIF), HIF hydroxylases and oxygen sensing.
द्वारा: Webb, J, और अन्य
प्रकाशित: (2009) -
Hypoxia-inducible factor (HIF) asparagine hydroxylase is identical to factor inhibiting HIF (FIH) and is related to the cupin structural family.
द्वारा: Hewitson, K, और अन्य
प्रकाशित: (2002)