Signalling hypoxia by HIF hydroxylases.

Signalling hypoxia by HIF hydroxylases.

Analysis of oxygen sensitive pathways that regulate the hypoxia inducible factor (HIF) transcriptional system has revealed a novel role for oxygenases in signalling hypoxia. The enzymes, which catalyse hydroxylation of specific prolyl and asparaginyl residues in the regulatory HIF-alpha subunits, be...

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Bibliografiska uppgifter
Huvudupphovsmän:	Schofield, C, Ratcliffe, P
Materialtyp:	Journal article
Språk:	English
Publicerad:	2005

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