Signalling hypoxia by HIF hydroxylases.

Signalling hypoxia by HIF hydroxylases.

Analysis of oxygen sensitive pathways that regulate the hypoxia inducible factor (HIF) transcriptional system has revealed a novel role for oxygenases in signalling hypoxia. The enzymes, which catalyse hydroxylation of specific prolyl and asparaginyl residues in the regulatory HIF-alpha subunits, be...

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Những tác giả chính:	Schofield, C, Ratcliffe, P
Định dạng:	Journal article
Ngôn ngữ:	English
Được phát hành:	2005

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