A novel high throughput screening platform reveals an optimised cytokine formulation for human hematopoietic progenitor cell expansion.

A novel high throughput screening platform reveals an optimised cytokine formulation for human hematopoietic progenitor cell expansion.

The main limitations of hematopoietic cord blood (CB) transplantation, viz. low cell dosage and delayed reconstitution, can be overcome by ex-vivo expansion. CB expansion under conventional culture causes the rapid cell differentiation and depletion of hematopoietic stem/progenitor cells (HSPC) resp...

وصف كامل

التفاصيل البيبلوغرافية
المؤلفون الرئيسيون:	Tarunina, M, Hernandez, D, Kronsteiner-Dobramysl, B, Pratt, P, Watson, T, Hua, P, Gullo, F, Van der Garde, M, Zhang, Y, Hook, L, Choo, Y, Watt, S
التنسيق:	Journal article
اللغة:	English
منشور في:	Mary Ann Liebert, Inc 2016

مواد مشابهة

Single-cell assessment of transcriptome alterations induced by Scriptaid in early differentiated human haematopoietic progenitors during ex vivo expansion
حسب: Hua, P, وآخرون
منشور في: (2019)

Cryopreservation of hematopoietic stem/progenitor cells for therapeutic use.
حسب: Watt, S, وآخرون
منشور في: (2007)

Tailored Cytokine Optimization for ex vivo Culture Platforms Targeting the Expansion of Human Hematopoietic Stem/Progenitor Cells
حسب: André Branco, وآخرون
منشور في: (2020-09-01)

Increasing complexity of molecular landscapes in human hematopoietic stem and progenitor cells during development and aging
حسب: Watt, SM, وآخرون
منشور في: (2022)

An improved medium formulation for efficient ex vivo gene editing, expansion and engraftment of hematopoietic stem and progenitor cells
حسب: Rajeev Rai, وآخرون
منشور في: (2023-06-01)

Gene expression profiles and cytokine environments determine the in vitro proliferation and expansion capacities of human hematopoietic stem and progenitor cells
حسب: Roberto Dircio-Maldonado, وآخرون
منشور في: (2022-12-01)

Potential marker subset of blood-circulating cytokines on hematopoietic progenitor-to-Th1 pathway in COVID-19
حسب: Yasuo Takashima, وآخرون
منشور في: (2024-02-01)

IN VIVO EFFECTS OF ELTROMBOPAG ON THE EXPANSION OF HEMATOPOIETIC STEM AND PROGENITOR CELLS IN APLASTIC ANAEMIA
حسب: B.Q. Oliveira, وآخرون
منشور في: (2020-11-01)

Optimized Intracellular Staining Reveals Heterogeneous Cytokine Production Ability of Murine and Human Hematopoietic Stem and Progenitor Cells
حسب: Shufeng Luo, وآخرون
منشور في: (2021-04-01)

Methylome of human senescent hematopoietic progenitors
حسب: Stephen Capone, وآخرون
منشور في: (2018-12-01)

Jam-a is highly expressed on human hematopoietic repopulating cells and associates with the key hematopoietic chemokine receptor cxcr4.
حسب: Watt, S, وآخرون
منشور في: (2016)

Competition between hematopoietic stem and progenitor cells controls hematopoietic stem cell compartment size
حسب: Runfeng Miao, وآخرون
منشور في: (2022-08-01)

Epigenetic Memories in Hematopoietic Stem and Progenitor Cells
حسب: Kazumasa Aoyama, وآخرون
منشور في: (2022-07-01)

Systems mapping for hematopoietic progenitor cell heterogeneity.
حسب: Linghua Zhou, وآخرون
منشور في: (2015-01-01)

Hematopoietic Stem and Progenitor Cells in Inflammation and Allergy
حسب: Kimberly D. Fischer, وآخرون
منشور في: (2013-12-01)

Quality of thawed hematopoietic progenitor cell grafts
حسب: Metka Krašna, وآخرون
منشور في: (2015-06-01)

Multipotent Hematopoietic Progenitors Divide Asymmetrically to Create Progenitors of the Lymphomyeloid and Erythromyeloid Lineages
حسب: André Görgens, وآخرون
منشور في: (2015-07-01)

Multipotent Hematopoietic Progenitors Divide Asymmetrically to Create Progenitors of the Lymphomyeloid and Erythromyeloid Lineages
حسب: André Görgens, وآخرون
منشور في: (2014-12-01)

Chemical Cocktail Induces Hematopoietic Reprogramming and Expands Hematopoietic Stem/Progenitor Cells
حسب: Yi Zhou, وآخرون
منشور في: (2020-01-01)

Microencapsulated Osteoblasts Support Hematopoietic Stem/Progenitor Cell Expansion in Hypoxic Environment
حسب: Ke-Dong, S, وآخرون
منشور في: (2010)

Fetal hepatic progenitors support long-term expansion of hematopoietic stem cells
حسب: Chou, Song, وآخرون
منشور في: (2016)

ANGPTL7 regulates the expansion and repopulation of human hematopoietic stem and progenitor cells
حسب: Yiren Xiao, وآخرون
منشور في: (2015-05-01)

Advances in ex vivo expansion of hematopoietic stem and progenitor cells for clinical applications
حسب: André Branco, وآخرون
منشور في: (2024-05-01)

Hematopoietic progenitor cells and interleukin-stimulated endothelium: expansion and differentiation of myeloid precursors
حسب: Kiesewetter Holger, وآخرون
منشور في: (2008-10-01)

Differential Reponses of Hematopoietic Stem and Progenitor Cells to mTOR Inhibition
حسب: Aimin Yang, وآخرون
منشور في: (2015-01-01)

p190-B RhoGAP and intracellular cytokine signals balance hematopoietic stem and progenitor cell self-renewal and differentiation
حسب: Ashwini Hinge, وآخرون
منشور في: (2017-02-01)

Immunomodulatory drugs downregulate IKZF1 leading to expansion of hematopoietic progenitors with concomitant block of megakaryocytic maturation
حسب: Ailing Liu, وآخرون
منشور في: (2018-10-01)

Ricolinostat promotes the generation of megakaryocyte progenitors from human hematopoietic stem and progenitor cells
حسب: Jianan Jiang, وآخرون
منشور في: (2022-02-01)

Transmembrane Inhibitor of RICTOR/mTORC2 in Hematopoietic Progenitors
حسب: Dongjun Lee, وآخرون
منشور في: (2014-11-01)

Generation and function of progenitor T cells from StemRegenin-1–expanded CD34+ human hematopoietic progenitor cells
حسب: Jastaranpreet Singh, وآخرون
منشور في: (2019-10-01)

A novel application for a 3-dimensional timelapse assay that distinguishes chemotactic from chemokinetic responses of hematopoietic CD133(+) stem/progenitor cells
حسب: Pepperell, E, وآخرون
منشور في: (2013)

Reciprocal upregulation of Notch signaling molecules in hematopoietic progenitor and mesenchymal stromal cells
حسب: Kikuchi Y, وآخرون
منشور في: (2011-01-01)

VEGF Receptor 1 Promotes Hypoxia-Induced Hematopoietic Progenitor Proliferation and Differentiation
حسب: Jonathan Florentin, وآخرون
منشور في: (2022-05-01)

Transplantation of hematopoietic progenitor cells with emphasis on the results in children
حسب: E D Thomas
منشور في: (1995-01-01)

Unbiased phenotypic identification of functionally distinct hematopoietic progenitors
حسب: Grigorios Georgolopoulos, وآخرون
منشور في: (2019-07-01)

Hematopoietic Stem/Progenitor Cells and the Pathogenesis of HIV/AIDS
حسب: Tetsuo Tsukamoto
منشور في: (2020-02-01)

Editorial: The Role of Hematopoietic Progenitors in Immune Regulation and Memory
حسب: Flora Zavala, وآخرون
منشور في: (2021-11-01)

Direct Reprogramming of Murine Fibroblasts to Hematopoietic Progenitor Cells
حسب: Kiran Batta, وآخرون
منشور في: (2014-12-01)

Irradiation selects for p53-deficient hematopoietic progenitors.
حسب: Andriy Marusyk, وآخرون
منشور في: (2010-03-01)

Hypoxia Regulates Lymphoid Development of Human Hematopoietic Progenitors
حسب: Sara Chabi, وآخرون
منشور في: (2019-11-01)