A novel high throughput screening platform reveals an optimised cytokine formulation for human hematopoietic progenitor cell expansion.

The main limitations of hematopoietic cord blood (CB) transplantation, viz. low cell dosage and delayed reconstitution, can be overcome by ex-vivo expansion. CB expansion under conventional culture causes the rapid cell differentiation and depletion of hematopoietic stem/progenitor cells (HSPC) resp...

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Autors principals: Tarunina, M, Hernandez, D, Kronsteiner-Dobramysl, B, Pratt, P, Watson, T, Hua, P, Gullo, F, Van der Garde, M, Zhang, Y, Hook, L, Choo, Y, Watt, S
Format: Journal article
Idioma:English
Publicat: Mary Ann Liebert, Inc 2016

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