A novel high throughput screening platform reveals an optimised cytokine formulation for human hematopoietic progenitor cell expansion.

A novel high throughput screening platform reveals an optimised cytokine formulation for human hematopoietic progenitor cell expansion.

The main limitations of hematopoietic cord blood (CB) transplantation, viz. low cell dosage and delayed reconstitution, can be overcome by ex-vivo expansion. CB expansion under conventional culture causes the rapid cell differentiation and depletion of hematopoietic stem/progenitor cells (HSPC) resp...

Descrición completa

Detalles Bibliográficos
Main Authors:	Tarunina, M, Hernandez, D, Kronsteiner-Dobramysl, B, Pratt, P, Watson, T, Hua, P, Gullo, F, Van der Garde, M, Zhang, Y, Hook, L, Choo, Y, Watt, S
Formato:	Journal article
Idioma:	English
Publicado:	Mary Ann Liebert, Inc 2016

Títulos similares

Single-cell assessment of transcriptome alterations induced by Scriptaid in early differentiated human haematopoietic progenitors during ex vivo expansion
por: Hua, P, et al.
Publicado: (2019)

Tailored Cytokine Optimization for ex vivo Culture Platforms Targeting the Expansion of Human Hematopoietic Stem/Progenitor Cells
por: André Branco, et al.
Publicado: (2020-09-01)

Gene expression profiles and cytokine environments determine the in vitro proliferation and expansion capacities of human hematopoietic stem and progenitor cells
por: Roberto Dircio-Maldonado, et al.
Publicado: (2022-12-01)

IN VIVO EFFECTS OF ELTROMBOPAG ON THE EXPANSION OF HEMATOPOIETIC STEM AND PROGENITOR CELLS IN APLASTIC ANAEMIA
por: B.Q. Oliveira, et al.
Publicado: (2020-11-01)

Cryopreservation of hematopoietic stem/progenitor cells for therapeutic use.
por: Watt, S, et al.
Publicado: (2007)

An improved medium formulation for efficient ex vivo gene editing, expansion and engraftment of hematopoietic stem and progenitor cells
por: Rajeev Rai, et al.
Publicado: (2023-06-01)

Microencapsulated Osteoblasts Support Hematopoietic Stem/Progenitor Cell Expansion in Hypoxic Environment
por: Ke-Dong, S, et al.
Publicado: (2010)

Fetal hepatic progenitors support long-term expansion of hematopoietic stem cells
por: Chou, Song, et al.
Publicado: (2016)

ANGPTL7 regulates the expansion and repopulation of human hematopoietic stem and progenitor cells
por: Yiren Xiao, et al.
Publicado: (2015-05-01)

Advances in ex vivo expansion of hematopoietic stem and progenitor cells for clinical applications
por: André Branco, et al.
Publicado: (2024-05-01)

Hematopoietic progenitor cells and interleukin-stimulated endothelium: expansion and differentiation of myeloid precursors
por: Kiesewetter Holger, et al.
Publicado: (2008-10-01)

Increasing complexity of molecular landscapes in human hematopoietic stem and progenitor cells during development and aging
por: Watt, SM, et al.
Publicado: (2022)

Immunomodulatory drugs downregulate IKZF1 leading to expansion of hematopoietic progenitors with concomitant block of megakaryocytic maturation
por: Ailing Liu, et al.
Publicado: (2018-10-01)

Mammalian target of rapamycin activity is required for expansion of CD34+ hematopoietic progenitor cells
por: Christian R. Geest, et al.
Publicado: (2009-07-01)

Serum after autologous transplantation stimulates proliferation and expansion of human hematopoietic progenitor cells.
por: Thomas Walenda, et al.
Publicado: (2011-01-01)

Generation, expansion, and drug treatment of hematopoietic progenitor cells derived from human iPSCs
por: Benjamin Dannenmann, et al.
Publicado: (2022-06-01)

Aberrant epigenetic regulators control expansion of human CD34+ hematopoietic stem/progenitor cells
por: Farnaz eFaridi, et al.
Publicado: (2013-11-01)

Potential marker subset of blood-circulating cytokines on hematopoietic progenitor-to-Th1 pathway in COVID-19
por: Yasuo Takashima, et al.
Publicado: (2024-02-01)

The combined influence of substrate elasticity and surface-grafted molecules on the exvivo expansion of hematopoietic stem and progenitor cells
por: Kumar, Suresh, et al.
Publicado: (2013)

Synergistic Integration of Mesenchymal Stem Cells and Hydrostatic Pressure in the Expansion and Maintenance of Human Hematopoietic/Progenitor Cells
por: Yun Gyeong Kang, et al.
Publicado: (2018-01-01)

FDA-Approved Drug Screening for Compounds That Facilitate Hematopoietic Stem and Progenitor Cells (HSPCs) Expansion in Zebrafish
por: Zhi Feng, et al.
Publicado: (2021-08-01)

Expansion of human cord blood hematopoietic stem/progenitor cells in three-dimensional Nanoscaffold coated with Fibronectin
por: Seyed Hadi Mousavi, et al.
Publicado: (2015-06-01)

Effects of encapsulated rabbit mesenchymal stem cells on ex vivo expansion of human umbilical cord blood hematopoietic stem/progenitor cells.
por: Liu, Y, et al.
Publicado: (2009)

Effects of encapsulated rabbit mesenchymal stem cells on ex vivo expansion of human umbilical cord blood hematopoietic stem/progenitor cells
por: Liu, Y, et al.
Publicado: (2007)

Methylome of human senescent hematopoietic progenitors
por: Stephen Capone, et al.
Publicado: (2018-12-01)

Sos1 deficiency ameliorates oncogenic KRAS-mediated hematopoietic stem cell exhaustion and myeloid progenitor expansion
por: Maoshuo Yang, et al.
Publicado: (2024-12-01)

Cord Blood-Derived Hematopoietic Stem/Progenitor Cells: Current Challenges in Engraftment, Infection, and Ex Vivo Expansion
por: Katsuhiro Kita, et al.
Publicado: (2011-01-01)

Competition between hematopoietic stem and progenitor cells controls hematopoietic stem cell compartment size
por: Runfeng Miao, et al.
Publicado: (2022-08-01)

Jam-a is highly expressed on human hematopoietic repopulating cells and associates with the key hematopoietic chemokine receptor cxcr4.
por: Watt, S, et al.
Publicado: (2016)

Multipotent Hematopoietic Progenitors Divide Asymmetrically to Create Progenitors of the Lymphomyeloid and Erythromyeloid Lineages
por: André Görgens, et al.
Publicado: (2015-07-01)

Multipotent Hematopoietic Progenitors Divide Asymmetrically to Create Progenitors of the Lymphomyeloid and Erythromyeloid Lineages
por: André Görgens, et al.
Publicado: (2014-12-01)

Epigenetic Memories in Hematopoietic Stem and Progenitor Cells
por: Kazumasa Aoyama, et al.
Publicado: (2022-07-01)

Systems mapping for hematopoietic progenitor cell heterogeneity.
por: Linghua Zhou, et al.
Publicado: (2015-01-01)

Hematopoietic Stem and Progenitor Cells in Inflammation and Allergy
por: Kimberly D. Fischer, et al.
Publicado: (2013-12-01)

Chemical Cocktail Induces Hematopoietic Reprogramming and Expands Hematopoietic Stem/Progenitor Cells
por: Yi Zhou, et al.
Publicado: (2020-01-01)

Effective expansion of umbilical cord blood hematopoietic stem/progenitor cells by regulation of microencapsulated osteoblasts under hypoxic condition.
por: Song, K, et al.
Publicado: (2009)

Ex vivo expansion of human umbilical cord blood hematopoietic stem/progenitor with support of microencapsulated rabbit mesenchymal stem cells in rotating wall vessel
por: Liu, Y, et al.
Publicado: (2007)

Differential Reponses of Hematopoietic Stem and Progenitor Cells to mTOR Inhibition
por: Aimin Yang, et al.
Publicado: (2015-01-01)

Bordetella pertussis Whole Cell Immunization, Unlike Acellular Immunization, Mimics Naïve Infection by Driving Hematopoietic Stem and Progenitor Cell Expansion in Mice
por: Melinda E. Varney, et al.
Publicado: (2018-10-01)

Ricolinostat promotes the generation of megakaryocyte progenitors from human hematopoietic stem and progenitor cells
por: Jianan Jiang, et al.
Publicado: (2022-02-01)