A novel high throughput screening platform reveals an optimised cytokine formulation for human hematopoietic progenitor cell expansion.

A novel high throughput screening platform reveals an optimised cytokine formulation for human hematopoietic progenitor cell expansion.

The main limitations of hematopoietic cord blood (CB) transplantation, viz. low cell dosage and delayed reconstitution, can be overcome by ex-vivo expansion. CB expansion under conventional culture causes the rapid cell differentiation and depletion of hematopoietic stem/progenitor cells (HSPC) resp...

Szczegółowa specyfikacja

Opis bibliograficzny
Główni autorzy:	Tarunina, M, Hernandez, D, Kronsteiner-Dobramysl, B, Pratt, P, Watson, T, Hua, P, Gullo, F, Van der Garde, M, Zhang, Y, Hook, L, Choo, Y, Watt, S
Format:	Journal article
Język:	English
Wydane:	Mary Ann Liebert, Inc 2016

Podobne zapisy

Single-cell assessment of transcriptome alterations induced by Scriptaid in early differentiated human haematopoietic progenitors during ex vivo expansion
od: Hua, P, i wsp.
Wydane: (2019)

Cryopreservation of hematopoietic stem/progenitor cells for therapeutic use.
od: Watt, S, i wsp.
Wydane: (2007)

Tailored Cytokine Optimization for ex vivo Culture Platforms Targeting the Expansion of Human Hematopoietic Stem/Progenitor Cells
od: André Branco, i wsp.
Wydane: (2020-09-01)

Increasing complexity of molecular landscapes in human hematopoietic stem and progenitor cells during development and aging
od: Watt, SM, i wsp.
Wydane: (2022)

An improved medium formulation for efficient ex vivo gene editing, expansion and engraftment of hematopoietic stem and progenitor cells
od: Rajeev Rai, i wsp.
Wydane: (2023-06-01)

Gene expression profiles and cytokine environments determine the in vitro proliferation and expansion capacities of human hematopoietic stem and progenitor cells
od: Roberto Dircio-Maldonado, i wsp.
Wydane: (2022-12-01)

Potential marker subset of blood-circulating cytokines on hematopoietic progenitor-to-Th1 pathway in COVID-19
od: Yasuo Takashima, i wsp.
Wydane: (2024-02-01)

IN VIVO EFFECTS OF ELTROMBOPAG ON THE EXPANSION OF HEMATOPOIETIC STEM AND PROGENITOR CELLS IN APLASTIC ANAEMIA
od: B.Q. Oliveira, i wsp.
Wydane: (2020-11-01)

Optimized Intracellular Staining Reveals Heterogeneous Cytokine Production Ability of Murine and Human Hematopoietic Stem and Progenitor Cells
od: Shufeng Luo, i wsp.
Wydane: (2021-04-01)

Methylome of human senescent hematopoietic progenitors
od: Stephen Capone, i wsp.
Wydane: (2018-12-01)

Jam-a is highly expressed on human hematopoietic repopulating cells and associates with the key hematopoietic chemokine receptor cxcr4.
od: Watt, S, i wsp.
Wydane: (2016)

Competition between hematopoietic stem and progenitor cells controls hematopoietic stem cell compartment size
od: Runfeng Miao, i wsp.
Wydane: (2022-08-01)

Epigenetic Memories in Hematopoietic Stem and Progenitor Cells
od: Kazumasa Aoyama, i wsp.
Wydane: (2022-07-01)

Systems mapping for hematopoietic progenitor cell heterogeneity.
od: Linghua Zhou, i wsp.
Wydane: (2015-01-01)

Hematopoietic Stem and Progenitor Cells in Inflammation and Allergy
od: Kimberly D. Fischer, i wsp.
Wydane: (2013-12-01)

Quality of thawed hematopoietic progenitor cell grafts
od: Metka Krašna, i wsp.
Wydane: (2015-06-01)

Multipotent Hematopoietic Progenitors Divide Asymmetrically to Create Progenitors of the Lymphomyeloid and Erythromyeloid Lineages
od: André Görgens, i wsp.
Wydane: (2015-07-01)

Multipotent Hematopoietic Progenitors Divide Asymmetrically to Create Progenitors of the Lymphomyeloid and Erythromyeloid Lineages
od: André Görgens, i wsp.
Wydane: (2014-12-01)

Chemical Cocktail Induces Hematopoietic Reprogramming and Expands Hematopoietic Stem/Progenitor Cells
od: Yi Zhou, i wsp.
Wydane: (2020-01-01)

Microencapsulated Osteoblasts Support Hematopoietic Stem/Progenitor Cell Expansion in Hypoxic Environment
od: Ke-Dong, S, i wsp.
Wydane: (2010)

Fetal hepatic progenitors support long-term expansion of hematopoietic stem cells
od: Chou, Song, i wsp.
Wydane: (2016)

ANGPTL7 regulates the expansion and repopulation of human hematopoietic stem and progenitor cells
od: Yiren Xiao, i wsp.
Wydane: (2015-05-01)

Advances in ex vivo expansion of hematopoietic stem and progenitor cells for clinical applications
od: André Branco, i wsp.
Wydane: (2024-05-01)

Hematopoietic progenitor cells and interleukin-stimulated endothelium: expansion and differentiation of myeloid precursors
od: Kiesewetter Holger, i wsp.
Wydane: (2008-10-01)

Differential Reponses of Hematopoietic Stem and Progenitor Cells to mTOR Inhibition
od: Aimin Yang, i wsp.
Wydane: (2015-01-01)

p190-B RhoGAP and intracellular cytokine signals balance hematopoietic stem and progenitor cell self-renewal and differentiation
od: Ashwini Hinge, i wsp.
Wydane: (2017-02-01)

Immunomodulatory drugs downregulate IKZF1 leading to expansion of hematopoietic progenitors with concomitant block of megakaryocytic maturation
od: Ailing Liu, i wsp.
Wydane: (2018-10-01)

Ricolinostat promotes the generation of megakaryocyte progenitors from human hematopoietic stem and progenitor cells
od: Jianan Jiang, i wsp.
Wydane: (2022-02-01)

Transmembrane Inhibitor of RICTOR/mTORC2 in Hematopoietic Progenitors
od: Dongjun Lee, i wsp.
Wydane: (2014-11-01)

Generation and function of progenitor T cells from StemRegenin-1–expanded CD34+ human hematopoietic progenitor cells
od: Jastaranpreet Singh, i wsp.
Wydane: (2019-10-01)

A novel application for a 3-dimensional timelapse assay that distinguishes chemotactic from chemokinetic responses of hematopoietic CD133(+) stem/progenitor cells
od: Pepperell, E, i wsp.
Wydane: (2013)

Reciprocal upregulation of Notch signaling molecules in hematopoietic progenitor and mesenchymal stromal cells
od: Kikuchi Y, i wsp.
Wydane: (2011-01-01)

VEGF Receptor 1 Promotes Hypoxia-Induced Hematopoietic Progenitor Proliferation and Differentiation
od: Jonathan Florentin, i wsp.
Wydane: (2022-05-01)

Transplantation of hematopoietic progenitor cells with emphasis on the results in children
od: E D Thomas
Wydane: (1995-01-01)

Unbiased phenotypic identification of functionally distinct hematopoietic progenitors
od: Grigorios Georgolopoulos, i wsp.
Wydane: (2019-07-01)

Hematopoietic Stem/Progenitor Cells and the Pathogenesis of HIV/AIDS
od: Tetsuo Tsukamoto
Wydane: (2020-02-01)

Editorial: The Role of Hematopoietic Progenitors in Immune Regulation and Memory
od: Flora Zavala, i wsp.
Wydane: (2021-11-01)

Direct Reprogramming of Murine Fibroblasts to Hematopoietic Progenitor Cells
od: Kiran Batta, i wsp.
Wydane: (2014-12-01)

Irradiation selects for p53-deficient hematopoietic progenitors.
od: Andriy Marusyk, i wsp.
Wydane: (2010-03-01)

Hypoxia Regulates Lymphoid Development of Human Hematopoietic Progenitors
od: Sara Chabi, i wsp.
Wydane: (2019-11-01)