A novel high throughput screening platform reveals an optimised cytokine formulation for human hematopoietic progenitor cell expansion.
The main limitations of hematopoietic cord blood (CB) transplantation, viz. low cell dosage and delayed reconstitution, can be overcome by ex-vivo expansion. CB expansion under conventional culture causes the rapid cell differentiation and depletion of hematopoietic stem/progenitor cells (HSPC) resp...
Главные авторы: | Tarunina, M, Hernandez, D, Kronsteiner-Dobramysl, B, Pratt, P, Watson, T, Hua, P, Gullo, F, Van der Garde, M, Zhang, Y, Hook, L, Choo, Y, Watt, S |
---|---|
Формат: | Journal article |
Язык: | English |
Опубликовано: |
Mary Ann Liebert, Inc
2016
|
Схожие документы
-
Single-cell assessment of transcriptome alterations induced by Scriptaid in early differentiated human haematopoietic progenitors during ex vivo expansion
по: Hua, P, и др.
Опубликовано: (2019) -
Cryopreservation of hematopoietic stem/progenitor cells for therapeutic use.
по: Watt, S, и др.
Опубликовано: (2007) -
Tailored Cytokine Optimization for ex vivo Culture Platforms Targeting the Expansion of Human Hematopoietic Stem/Progenitor Cells
по: André Branco, и др.
Опубликовано: (2020-09-01) -
Increasing complexity of molecular landscapes in human hematopoietic stem and progenitor cells during development and aging
по: Watt, SM, и др.
Опубликовано: (2022) -
An improved medium formulation for efficient ex vivo gene editing, expansion and engraftment of hematopoietic stem and progenitor cells
по: Rajeev Rai, и др.
Опубликовано: (2023-06-01)