A novel high throughput screening platform reveals an optimised cytokine formulation for human hematopoietic progenitor cell expansion.
The main limitations of hematopoietic cord blood (CB) transplantation, viz. low cell dosage and delayed reconstitution, can be overcome by ex-vivo expansion. CB expansion under conventional culture causes the rapid cell differentiation and depletion of hematopoietic stem/progenitor cells (HSPC) resp...
Main Authors: | Tarunina, M, Hernandez, D, Kronsteiner-Dobramysl, B, Pratt, P, Watson, T, Hua, P, Gullo, F, Van der Garde, M, Zhang, Y, Hook, L, Choo, Y, Watt, S |
---|---|
格式: | Journal article |
語言: | English |
出版: |
Mary Ann Liebert, Inc
2016
|
相似書籍
-
Single-cell assessment of transcriptome alterations induced by Scriptaid in early differentiated human haematopoietic progenitors during ex vivo expansion
由: Hua, P, et al.
出版: (2019) -
Tailored Cytokine Optimization for ex vivo Culture Platforms Targeting the Expansion of Human Hematopoietic Stem/Progenitor Cells
由: André Branco, et al.
出版: (2020-09-01) -
Gene expression profiles and cytokine environments determine the in vitro proliferation and expansion capacities of human hematopoietic stem and progenitor cells
由: Roberto Dircio-Maldonado, et al.
出版: (2022-12-01) -
IN VIVO EFFECTS OF ELTROMBOPAG ON THE EXPANSION OF HEMATOPOIETIC STEM AND PROGENITOR CELLS IN APLASTIC ANAEMIA
由: B.Q. Oliveira, et al.
出版: (2020-11-01) -
Cryopreservation of hematopoietic stem/progenitor cells for therapeutic use.
由: Watt, S, et al.
出版: (2007)