Factor-inhibiting hypoxia-inducible factor (FIH) catalyses the post-translational hydroxylation of histidinyl residues within ankyrin repeat domains.

Factor-inhibiting hypoxia-inducible factor (FIH) is an Fe(II)/2-oxoglutarate-dependent dioxygenase that acts as a negative regulator of the hypoxia-inducible factor (HIF) by catalysing β-hydroxylation of an asparaginyl residue in its C-terminal transcriptional activation domain (CAD). In addition to...

সম্পূর্ণ বিবরণ

গ্রন্থ-পঞ্জীর বিবরন
প্রধান লেখক: Yang, M, Chowdhury, R, Ge, W, Hamed, R, McDonough, M, Claridge, T, Kessler, B, Cockman, M, Ratcliffe, P, Schofield, C
বিন্যাস: Journal article
ভাষা:English
প্রকাশিত: 2011