Water gated contrast switching with polymer–silica hybrid nanoparticles
Bioresponsive contrast agents can provide smart signaling in MRI. In wrapping pore functionalised Gd-DOTA mesoporous silica nanoparticles with pH-responsive poly(acrylic acid), exchange between pore and bulk water can be reversibly switched by local pH. The generated high contrast then exhibits a la...
Main Authors: | Pellico, J, Ellis, CM, Miller, J, Davis, JJ |
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Format: | Journal article |
Language: | English |
Published: |
Royal Society of Chemistry
2019
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