Water gated contrast switching with polymer–silica hybrid nanoparticles

Bioresponsive contrast agents can provide smart signaling in MRI. In wrapping pore functionalised Gd-DOTA mesoporous silica nanoparticles with pH-responsive poly(acrylic acid), exchange between pore and bulk water can be reversibly switched by local pH. The generated high contrast then exhibits a la...

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Bibliographic Details
Main Authors: Pellico, J, Ellis, CM, Miller, J, Davis, JJ
Format: Journal article
Language:English
Published: Royal Society of Chemistry 2019

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