Investigation into the regulatory mechanism of BRCA2 stability
<p>Inherited mutations in the BRCA2 gene predispose individuals to the development of breast and ovarian cancers. The BRCA2 protein plays a fundamental role in the repair of DNA double strand breaks by homologous recombination (HR). BRCA2 mediates the recruitment of the RAD51 recombinase to DN...
Автор: | Gruber, C |
---|---|
Інші автори: | Esashi, F |
Формат: | Дисертація |
Мова: | English |
Опубліковано: |
2013
|
Предмети: |
Схожі ресурси
-
Tet2 and relevant potential intervention in cancer
за авторством: Zauri, M
Опубліковано: (2014) -
DNA damage responses to loss of telomere integrity
за авторством: Carlos, AR
Опубліковано: (2013) -
Mechanism underlying follicular hyperproliferation and oncogenesis in hidradenitis suppurativa
за авторством: Lin Jin, та інші
Опубліковано: (2023-06-01) -
Novel regulation of SRC family kinase signalling by RASSF1 isoforms
за авторством: Scrace, SF
Опубліковано: (2013) -
SHP2 allosteric inhibitor TK-453 alleviates psoriasis-like skin inflammation in mice via inhibition of IL-23/Th17 axis
за авторством: Meijing Wang, та інші
Опубліковано: (2022-04-01)