Investigation into the regulatory mechanism of BRCA2 stability
<p>Inherited mutations in the BRCA2 gene predispose individuals to the development of breast and ovarian cancers. The BRCA2 protein plays a fundamental role in the repair of DNA double strand breaks by homologous recombination (HR). BRCA2 mediates the recruitment of the RAD51 recombinase to DN...
Κύριος συγγραφέας: | Gruber, C |
---|---|
Άλλοι συγγραφείς: | Esashi, F |
Μορφή: | Thesis |
Γλώσσα: | English |
Έκδοση: |
2013
|
Θέματα: |
Παρόμοια τεκμήρια
-
Tet2 and relevant potential intervention in cancer
ανά: Zauri, M
Έκδοση: (2014) -
DNA damage responses to loss of telomere integrity
ανά: Carlos, AR
Έκδοση: (2013) -
Mechanism underlying follicular hyperproliferation and oncogenesis in hidradenitis suppurativa
ανά: Lin Jin, κ.ά.
Έκδοση: (2023-06-01) -
Novel regulation of SRC family kinase signalling by RASSF1 isoforms
ανά: Scrace, SF
Έκδοση: (2013) -
SHP2 allosteric inhibitor TK-453 alleviates psoriasis-like skin inflammation in mice via inhibition of IL-23/Th17 axis
ανά: Meijing Wang, κ.ά.
Έκδοση: (2022-04-01)