Investigation into the regulatory mechanism of BRCA2 stability

<p>Inherited mutations in the BRCA2 gene predispose individuals to the development of breast and ovarian cancers. The BRCA2 protein plays a fundamental role in the repair of DNA double strand breaks by homologous recombination (HR). BRCA2 mediates the recruitment of the RAD51 recombinase to DN...

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Dettagli Bibliografici
Autore principale: Gruber, C
Altri autori: Esashi, F
Natura: Tesi
Lingua:English
Pubblicazione: 2013
Soggetti:

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