Investigation into the regulatory mechanism of BRCA2 stability

Investigation into the regulatory mechanism of BRCA2 stability

<p>Inherited mutations in the BRCA2 gene predispose individuals to the development of breast and ovarian cancers. The BRCA2 protein plays a fundamental role in the repair of DNA double strand breaks by homologous recombination (HR). BRCA2 mediates the recruitment of the RAD51 recombinase to DN...

Полное описание

Библиографические подробности
Главный автор:	Gruber, C
Другие авторы:	Esashi, F
Формат:	Диссертация
Язык:	English
Опубликовано:	2013
Предметы:	Medical Sciences Biology (medical sciences) Biochemistry DNA damage signalling

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