Investigation into the regulatory mechanism of BRCA2 stability

Investigation into the regulatory mechanism of BRCA2 stability

<p>Inherited mutations in the BRCA2 gene predispose individuals to the development of breast and ovarian cancers. The BRCA2 protein plays a fundamental role in the repair of DNA double strand breaks by homologous recombination (HR). BRCA2 mediates the recruitment of the RAD51 recombinase to DN...

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Chi tiết về thư mục
Tác giả chính:	Gruber, C
Tác giả khác:	Esashi, F
Định dạng:	Luận văn
Ngôn ngữ:	English
Được phát hành:	2013
Những chủ đề:	Medical Sciences Biology (medical sciences) Biochemistry DNA damage signalling

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