Investigation into the regulatory mechanism of BRCA2 stability

<p>Inherited mutations in the BRCA2 gene predispose individuals to the development of breast and ovarian cancers. The BRCA2 protein plays a fundamental role in the repair of DNA double strand breaks by homologous recombination (HR). BRCA2 mediates the recruitment of the RAD51 recombinase to DN...

Disgrifiad llawn

Manylion Llyfryddiaeth
Prif Awdur: Gruber, C
Awduron Eraill: Esashi, F
Fformat: Traethawd Ymchwil
Iaith:English
Cyhoeddwyd: 2013
Pynciau: