d-Amino acid oxidase and serine racemase in human brain: normal distribution and altered expression in schizophrenia.

d-Amino acid oxidase and serine racemase in human brain: normal distribution and altered expression in schizophrenia.

The N-methyl-D-aspartate receptor co-agonist d-serine is synthesized by serine racemase and degraded by D-amino acid oxidase. Both D-serine and its metabolizing enzymes are implicated in N-methyl-D-aspartate receptor hypofunction thought to occur in schizophrenia. We studied D-amino acid oxidase and...

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Bibliographic Details
Main Authors:	Verrall, L, Walker, M, Rawlings, N, Benzel, I, Kew, J, Harrison, P, Burnet, P
Format:	Journal article
Language:	English
Published:	2007

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