Shape-tension coupling produces nematic order in an epithelium vertex model
We study the vertex model for epithelial tissue mechanics extended to include coupling between the cell shapes and tensions in cell-cell junctions. This coupling represents an active force which drives the system out of equilibrium and leads to the formation of nematic order interspersed with promin...
| Main Authors: | , , |
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| Format: | Journal article |
| Language: | English |
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American Physical Society
2023
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| _version_ | 1797112077291094016 |
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| author | Rozman, J Yeomans, JM Sknepnek, R |
| author_facet | Rozman, J Yeomans, JM Sknepnek, R |
| author_sort | Rozman, J |
| collection | OXFORD |
| description | We study the vertex model for epithelial tissue mechanics extended to include coupling between the cell shapes and tensions in cell-cell junctions. This coupling represents an active force which drives the system out of equilibrium and leads to the formation of nematic order interspersed with prominent, long-lived +1 defects. The defects in the nematic ordering are coupled to the shape of the cell tiling, affecting cell areas and coordinations. This intricate interplay between cell shape, size, and coordination provides a possible mechanism by which tissues could spontaneously develop long-range polarity through local mechanical forces without resorting to long-range chemical patterning. |
| first_indexed | 2024-03-07T08:19:22Z |
| format | Journal article |
| id | oxford-uuid:e6bbc56b-068d-43c6-be16-5285b77fd874 |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-07T08:19:22Z |
| publishDate | 2023 |
| publisher | American Physical Society |
| record_format | dspace |
| spelling | oxford-uuid:e6bbc56b-068d-43c6-be16-5285b77fd8742024-01-16T11:30:41ZShape-tension coupling produces nematic order in an epithelium vertex modelJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:e6bbc56b-068d-43c6-be16-5285b77fd874EnglishSymplectic ElementsAmerican Physical Society2023Rozman, JYeomans, JMSknepnek, RWe study the vertex model for epithelial tissue mechanics extended to include coupling between the cell shapes and tensions in cell-cell junctions. This coupling represents an active force which drives the system out of equilibrium and leads to the formation of nematic order interspersed with prominent, long-lived +1 defects. The defects in the nematic ordering are coupled to the shape of the cell tiling, affecting cell areas and coordinations. This intricate interplay between cell shape, size, and coordination provides a possible mechanism by which tissues could spontaneously develop long-range polarity through local mechanical forces without resorting to long-range chemical patterning. |
| spellingShingle | Rozman, J Yeomans, JM Sknepnek, R Shape-tension coupling produces nematic order in an epithelium vertex model |
| title | Shape-tension coupling produces nematic order in an epithelium vertex model |
| title_full | Shape-tension coupling produces nematic order in an epithelium vertex model |
| title_fullStr | Shape-tension coupling produces nematic order in an epithelium vertex model |
| title_full_unstemmed | Shape-tension coupling produces nematic order in an epithelium vertex model |
| title_short | Shape-tension coupling produces nematic order in an epithelium vertex model |
| title_sort | shape tension coupling produces nematic order in an epithelium vertex model |
| work_keys_str_mv | AT rozmanj shapetensioncouplingproducesnematicorderinanepitheliumvertexmodel AT yeomansjm shapetensioncouplingproducesnematicorderinanepitheliumvertexmodel AT sknepnekr shapetensioncouplingproducesnematicorderinanepitheliumvertexmodel |