Use of HLA-B27 tetramers to identify low-frequency antigen-specific T cells in Chlamydia-triggered reactive arthritis.

Reports of the use of HLA-B27/peptide tetrameric complexes to study peptide-specific CD8+ T cells in HLA-B27+-related diseases are rare. To establish HLA-B27 tetramers we first compared the function of HLA-B27 tetramers with HLA-A2 tetramers by using viral epitopes. HLA-B27 and HLA-A2 tetramers load...

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書目詳細資料
Main Authors: Appel, H, Kuon, W, Kuhne, M, Wu, P, Kuhlmann, S, Kollnberger, S, Thiel, A, Bowness, P, Sieper, J
格式: Journal article
語言:English
出版: BioMed Central 2004