Use of HLA-B27 tetramers to identify low-frequency antigen-specific T cells in Chlamydia-triggered reactive arthritis.

Use of HLA-B27 tetramers to identify low-frequency antigen-specific T cells in Chlamydia-triggered reactive arthritis.

Show other versions (1)

Reports of the use of HLA-B27/peptide tetrameric complexes to study peptide-specific CD8+ T cells in HLA-B27+-related diseases are rare. To establish HLA-B27 tetramers we first compared the function of HLA-B27 tetramers with HLA-A2 tetramers by using viral epitopes. HLA-B27 and HLA-A2 tetramers load...

Full description

Bibliographic Details
Main Authors:	Appel, H, Kuon, W, Kuhne, M, Wu, P, Kuhlmann, S, Kollnberger, S, Thiel, A, Bowness, P, Sieper, J
Format:	Journal article
Language:	English
Published:	BioMed Central 2004

Similar Items

Use of HLA-B27 tetramers to identify low-frequency antigen-specific T cells in Chlamydia-triggered reactive arthritis.
by: Appel, H, et al.
Published: (2004)

Residue Cys-67 of HLA-B27 contributes to antigen presentation and T cell recognition of HLA-B27 restricted T cell epitopes.
by: Appel, H, et al.
Published: (2004)

The solvent-inaccessible Cys67 residue of HLA-B27 contributes to T cell recognition of HLA-B27/peptide complexes.
by: Appel, H, et al.
Published: (2004)

Identification of HLA-B27-restricted peptides from the Chlamydia trachomatis proteome with possible relevance to HLA-B27-associated diseases.
by: Kuon, W, et al.
Published: (2001)

HLA-B27-RESTRICTED PEPTIDE PRESENTATION TO CYTOTOXIC T-CELLS IN REACTIVE ARTHRITIS
by: Bowness, P, et al.
Published: (1995)

Dimers are forever. Expression and recognition of abnormal HLA-B27 in spondylo arthritis
by: Bowness, P, et al.
Published: (2005)

The KIRs of HLA-B27: the role of HLA-B27 KIR interactions in infection and spondyloarthritis
by: Wong-Baeza, I, et al.
Published: (2011)

HLA-B27
by: Bowness, P
Published: (2015)

EXPRESSION OF HLA-B27 HEAVY CHAIN FORMS IN ANKYLOSING SPONDYLITIS AND HLA-B27 POSITIVE CELL LINES
by: Rysnik, O, et al.
Published: (2012)

TARGETING MONOCYTE-EXPRESSED HLA-B27 HOMODIMERS IN ANKYLOSING SPONDYLITIS
by: Bowness, P, et al.
Published: (2010)

TARGETING MONOCYTE-EXPRESSED HLA-B27 HOMODIMERS IN ANKYLOSING SPONDYLITIS
by: Bowness, P, et al.
Published: (2010)

Functional characterisation of HLA-B27 in autoimmunity
by: Kollnberger, S, et al.
Published: (2001)

ENDOPLASMIC RETICULUM AMINOPEPTIDASE-1 (ERAP1) PLAYS A CRITICAL ROLE IN PEPTIDE BINDING AND ANTIGEN PRESENTATION BY HLA-B27
by: Chen, L, et al.
Published: (2012)

HLA-B27 transgenic rodents express cell surface HLA-B27 heavy chain homodimers and multimers.
by: Bowness, P, et al.
Published: (2003)

Direct visualisation of HLA-B27 forms in cell lines and Spondyloarthropathy tissues
by: Rysnik, O, et al.
Published: (2013)

THE ARTHRITIS-ASSOCIATED HLA-B(star)27:05 FORMS MORE CELL SURFACE B27 DIMER AND FREE HEAVY CHAIN LIGANDS FOR KIR3DL2 AND LILRB2 IMMUNORECEPTORS THAN HLA(star)B27:09
by: Shaw, J, et al.
Published: (2013)

HLA-B-27 heavy chain homodimer formation and natural killer cell family interaction - comparison of two HLA-B-27 subtypes in vitro
by: Giles, J, et al.
Published: (2008)

Identification and characterisation of cell surface HLA-B27 homodimers
by: Bird, L, et al.
Published: (2002)

Conserved TCR beta chain usage in reactive arthritis; evidence for selection by a putative HLA-B27-associated autoantigen.
by: May, E, et al.
Published: (2002)

The role of HLA-B27 interactions with natural killer receptors in the pathogenesis of spondyloarthritis
by: Kollnberger, S, et al.
Published: (2007)

The arrival of HLA class II tetramers.
by: Mcmichael, A, et al.
Published: (1999)

HLA-B27 HEAVY CHAIN DIMER EXPRESSION IN SPONDYLOARTHRITIS
by: Rysnik, O, et al.
Published: (2012)

The role of HLA-B27 in spondyloarthritis.
by: Allen, R, et al.
Published: (1999)

Molecular determinants for KIR3DL2 binding to HLA-B27 and other HLA-class I ligands
by: Hatano, H, et al.
Published: (2013)

The pathogenesis of spondyloarthritides - HLA-B-27 homodimer expression on human monocyte/macrophage cell lines
by: McHugh, K, et al.
Published: (2008)

HLA-B27 heavy chain homodimers are expressed in HLA-B27 transgenic rodent models of spondyloarthritis and are ligands for paired Ig-like receptors.
by: Kollnberger, S, et al.
Published: (2004)

Jekyll and Hyde: the transformation of HLA-B27.
by: Edwards, J, et al.
Published: (2000)

Cell-surface expression and immune receptor recognition of HLA-B27 homodimers.
by: Kollnberger, S, et al.
Published: (2002)

Expression of aberrant HLA-B27 molecules is dependent on B27 dosage and peptide supply.
by: McHugh, K, et al.
Published: (2014)

HLA-B27 homodimers differ in their interactions with LILRB1, LILRB2, KIR3DL1 and KIR3DL2 compared to HLA-B27 heterotrimers
by: Giles, J, et al.
Published: (2010)

The arthritis-associated HLA-B*27:05 allele forms more cell surface B27 dimer and free heavy chain ligands for KIR3DL2 than HLA-B*27:09.
by: Cauli, A, et al.
Published: (2013)

Interaction of HLA-B27 homodimers with KIR3DL1 and KIR3DL2, unlike HLA-B27 heterotrimers, is independent of the sequence of bound peptide.
by: Kollnberger, S, et al.
Published: (2007)

Lymphoblastoid cells express HLA-B27 homodimers both intracellularly and at the cell surface following endosomal recycling.
by: Bird, L, et al.
Published: (2003)

HLA B27 in health and disease: a double-edged sword?
by: Bowness, P
Published: (2002)

Inhibiting HLA-B27 homodimer-driven immune cell inflammation in spondylarthritis.
by: Payeli, S, et al.
Published: (2012)

CELL SURFACE EXPRESSION OF HLA B27 HEAVY CHAINS AND SPECIFIC RECOGNITION BY IMMUNE RECEPTORS, POSSIBLE ROLE IN SPONDYLOARTHROPATHY
by: Kollnberger, S, et al.
Published: (2002)

The biochemistry and immunology of non-canonical forms of HLA-B27
by: Shaw, J, et al.
Published: (2014)

HLA-B27: natural function and pathogenic role in spondyloarthritis.
by: McMichael, A, et al.
Published: (2002)

HLA class I-minor histocompatibility antigen tetramers select cytotoxic T cells with high avidity to the natural ligand.
by: Gillespie, G, et al.
Published: (2000)

THE ROLE OF HLA-B27 KIR3DL2 INTERACTIONS IN THE PATHOGENESIS OF SPONDYLOARTHRITIS
by: Kollnberger, S, et al.
Published: (2012)