Defective presentation to class I-restricted cytotoxic T lymphocytes in vaccinia-infected cells is overcome by enhanced degradation of antigen.
Vaccinia infection interferes with the presentation of influenza Haemagglutinin (HA) and Nucleoprotein (NP) to class I-restricted CTL. The inhibitory effect is selective for certain epitopes, and is more profound during the late phase of infection. For influenza A/NT/60/68 NP, the block is present d...
Κύριοι συγγραφείς: | Townsend, A, Bastin, J, Gould, K, Brownlee, G, Andrew, M, Coupar, B, Boyle, D, Chan, S, Smith, G |
---|---|
Μορφή: | Journal article |
Γλώσσα: | English |
Έκδοση: |
1988
|
Παρόμοια τεκμήρια
Παρόμοια τεκμήρια
-
Vaccinia virus serpins B13R and B22R do not inhibit antigen presentation to class I-restricted cytotoxic T lymphocytes.
ανά: Blake, N, κ.ά.
Έκδοση: (1995) -
A 15 amino acid fragment of influenza nucleoprotein synthesized in the cytoplasm is presented to class I-restricted cytotoxic T lymphocytes.
ανά: Gould, K, κ.ά.
Έκδοση: (1989) -
DO VACCINIA VIRUS-ENCODED SERPINS INHIBIT ANTIGEN PRESENTATION TO CLASS I-RESTRICTED CTL
ανά: Blake, N, κ.ά.
Έκδοση: (1993) -
Cytotoxic T lymphocytes recognize influenza haemagglutinin that lacks a signal sequence
ανά: Townsend, A, κ.ά.
Έκδοση: (1986) -
Mouse H-2(k)-restricted cytotoxic T cells recognize antigenic determinants in both the HA1 and HA2 subunits of the influenza A/PR/8/34 hemagglutinin
ανά: Gould, K, κ.ά.
Έκδοση: (1987)