Defective presentation to class I-restricted cytotoxic T lymphocytes in vaccinia-infected cells is overcome by enhanced degradation of antigen.

Defective presentation to class I-restricted cytotoxic T lymphocytes in vaccinia-infected cells is overcome by enhanced degradation of antigen.

Vaccinia infection interferes with the presentation of influenza Haemagglutinin (HA) and Nucleoprotein (NP) to class I-restricted CTL. The inhibitory effect is selective for certain epitopes, and is more profound during the late phase of infection. For influenza A/NT/60/68 NP, the block is present d...

书目详细资料
Main Authors:	Townsend, A, Bastin, J, Gould, K, Brownlee, G, Andrew, M, Coupar, B, Boyle, D, Chan, S, Smith, G
格式:	Journal article
语言:	English
出版:	1988

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