In vivo quantification of VCAM-1 expression in renal ischemia reperfusion injury using non-invasive magnetic resonance molecular imaging.

RATIONALE AND OBJECTIVE: Vascular cell adhesion molecule-1 (VCAM-1) is upregulated in ischemia reperfusion injury (IRI), persisting after restoration of blood flow. We hypothesized that microparticles of iron oxide targeting VCAM-1 (VCAM-MPIO) would depict "ischemic memory" and enable in...

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Detalles Bibliográficos
Autores principales: Akhtar, A, Schneider, J, Chapman, S, Jefferson, A, Digby, J, Mankia, K, Chen, Y, McAteer, M, Wood, K, Choudhury, R
Formato: Journal article
Lenguaje:English
Publicado: Public Library of Science 2010