Conformational dynamics of M2 helices in KirBac channels: helix flexibility in relation to gating via molecular dynamics simulations.

Conformational dynamics of M2 helices in KirBac channels: helix flexibility in relation to gating via molecular dynamics simulations.

KirBac1.1 and 3.1 are bacterial homologues of mammalian inward rectifier K channels. We have performed extended molecular dynamics simulations (five simulations, each of >20 ns duration) of the transmembrane domain of KirBac in two membrane environments, a palmitoyl oleoyl phosphatidylcholine...

Disgrifiad llawn

Manylion Llyfryddiaeth
Prif Awduron:	Grottesi, A, Domene, C, Hall, B, Sansom, MS
Fformat:	Journal article
Iaith:	English
Cyhoeddwyd:	2005

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