Stimulation of the KATP channel by ADP and diazoxide requires nucleotide hydrolysis in mouse pancreatic beta-cells.

1. The mechanisms by which ADP and the hyperglycaemic compound diazoxide stimulate the activity of the ATP-regulated K+ channel (KATP channel) were studied using inside-out patches isolated from mouse pancreatic beta-cells maintained in tissue culture. 2. The ability of diazoxide and ADP to increase...

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Hlavní autoři: Larsson, O, Ammälä, C, Bokvist, K, Fredholm, B, Rorsman, P
Médium: Journal article
Jazyk:English
Vydáno: 1993