Tuberculosis vaccines in the era of Covid-19 - what is taking us so long?

The Mycobacterium bovis BCG vaccine was first used in 1921, but has not controlled the global spread of tuberculosis (TB). There are still no new licensed tuberculosis vaccines, although there much active research and a vaccine development pipeline, with vaccines designed to prevent infection, preve...

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Main Authors: Dockrell, HM, McShane, H
Format: Journal article
Language:English
Published: Elsevier 2022
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author Dockrell, HM
McShane, H
author_facet Dockrell, HM
McShane, H
author_sort Dockrell, HM
collection OXFORD
description The Mycobacterium bovis BCG vaccine was first used in 1921, but has not controlled the global spread of tuberculosis (TB). There are still no new licensed tuberculosis vaccines, although there much active research and a vaccine development pipeline, with vaccines designed to prevent infection, prevent disease, or accelerate TB treatment. These vaccines are of different types, and designed to replace BCG, or to boost immunity following BCG vaccination. This viewpoint discusses why, when it has been possible to develop new vaccines for SARS-CoV-2 so quickly, it is taking so long to develop new tuberculosis vaccines.
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spelling oxford-uuid:e7493475-6bf5-491d-8ec6-71679a8e68892022-06-10T06:56:57ZTuberculosis vaccines in the era of Covid-19 - what is taking us so long?Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:e7493475-6bf5-491d-8ec6-71679a8e6889EnglishSymplectic ElementsElsevier2022Dockrell, HMMcShane, HThe Mycobacterium bovis BCG vaccine was first used in 1921, but has not controlled the global spread of tuberculosis (TB). There are still no new licensed tuberculosis vaccines, although there much active research and a vaccine development pipeline, with vaccines designed to prevent infection, prevent disease, or accelerate TB treatment. These vaccines are of different types, and designed to replace BCG, or to boost immunity following BCG vaccination. This viewpoint discusses why, when it has been possible to develop new vaccines for SARS-CoV-2 so quickly, it is taking so long to develop new tuberculosis vaccines.
spellingShingle Dockrell, HM
McShane, H
Tuberculosis vaccines in the era of Covid-19 - what is taking us so long?
title Tuberculosis vaccines in the era of Covid-19 - what is taking us so long?
title_full Tuberculosis vaccines in the era of Covid-19 - what is taking us so long?
title_fullStr Tuberculosis vaccines in the era of Covid-19 - what is taking us so long?
title_full_unstemmed Tuberculosis vaccines in the era of Covid-19 - what is taking us so long?
title_short Tuberculosis vaccines in the era of Covid-19 - what is taking us so long?
title_sort tuberculosis vaccines in the era of covid 19 what is taking us so long
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AT mcshaneh tuberculosisvaccinesintheeraofcovid19whatistakingussolong