Plk1 negatively regulates Cep55 recruitment to the midbody to ensure orderly abscission.

Cytokinesis requires a membrane-remodeling and fission event termed abscission that occurs after chromosome segregation, cleavage furrow formation, and contraction have completed. In this study, we show how abscission factor recruitment is controlled by the Polo-like kinase 1 (Plk1). At the metaphas...

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Hlavní autoři: Bastos, R, Barr, F
Médium: Journal article
Jazyk:English
Vydáno: 2010