Just pretty pictures? What diffusion tractography can add in clinical neuroscience.

PURPOSE OF REVIEW: Diffusion tractography uses non-invasive brain imaging data to trace fibre bundles in the human brain in vivo. This raises immediate possibilities for clinical application but responsible use of this approach requires careful consideration of the scope and limitations of the techn...

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Main Authors: Johansen-Berg, H, Behrens, T
Format: Journal article
Language:English
Published: 2006
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author Johansen-Berg, H
Behrens, T
author_facet Johansen-Berg, H
Behrens, T
author_sort Johansen-Berg, H
collection OXFORD
description PURPOSE OF REVIEW: Diffusion tractography uses non-invasive brain imaging data to trace fibre bundles in the human brain in vivo. This raises immediate possibilities for clinical application but responsible use of this approach requires careful consideration of the scope and limitations of the technique. RECENT FINDINGS: To illustrate the potential for tractography to provide new information in clinical neuroscience we review recent studies in three broad areas: use of tractography for quantitative comparisons of specific white matter pathways in disease; evidence from tractography for the presence of qualitatively different pathways in congenital disorders or following recovery; use of tractography to gain insights into normal brain anatomy that can aid our understanding of the consequences of localised pathology, or guide interventions. SUMMARY: Diffusion tractography opens exciting new possibilities for exploring features of brain anatomy that previously were not visible to us in vivo.
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spelling oxford-uuid:e75be7ea-03cd-49ee-90ff-0438a5633e2b2022-03-27T10:37:57ZJust pretty pictures? What diffusion tractography can add in clinical neuroscience.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:e75be7ea-03cd-49ee-90ff-0438a5633e2bEnglishSymplectic Elements at Oxford2006Johansen-Berg, HBehrens, TPURPOSE OF REVIEW: Diffusion tractography uses non-invasive brain imaging data to trace fibre bundles in the human brain in vivo. This raises immediate possibilities for clinical application but responsible use of this approach requires careful consideration of the scope and limitations of the technique. RECENT FINDINGS: To illustrate the potential for tractography to provide new information in clinical neuroscience we review recent studies in three broad areas: use of tractography for quantitative comparisons of specific white matter pathways in disease; evidence from tractography for the presence of qualitatively different pathways in congenital disorders or following recovery; use of tractography to gain insights into normal brain anatomy that can aid our understanding of the consequences of localised pathology, or guide interventions. SUMMARY: Diffusion tractography opens exciting new possibilities for exploring features of brain anatomy that previously were not visible to us in vivo.
spellingShingle Johansen-Berg, H
Behrens, T
Just pretty pictures? What diffusion tractography can add in clinical neuroscience.
title Just pretty pictures? What diffusion tractography can add in clinical neuroscience.
title_full Just pretty pictures? What diffusion tractography can add in clinical neuroscience.
title_fullStr Just pretty pictures? What diffusion tractography can add in clinical neuroscience.
title_full_unstemmed Just pretty pictures? What diffusion tractography can add in clinical neuroscience.
title_short Just pretty pictures? What diffusion tractography can add in clinical neuroscience.
title_sort just pretty pictures what diffusion tractography can add in clinical neuroscience
work_keys_str_mv AT johansenbergh justprettypictureswhatdiffusiontractographycanaddinclinicalneuroscience
AT behrenst justprettypictureswhatdiffusiontractographycanaddinclinicalneuroscience