Characterising the role of circulating immune cells in brain metastasis

Characterising the role of circulating immune cells in brain metastasis

<p>Brain metastasis is a frequent occurrence in cancer patients and carries a high mortality rate. The incidence of brain metastasis is on the rise, highlighting the need for improved therapeutic intervention. Immune cells have been shown to promote disseminated tumour cells to colonise the l...

Fuld beskrivelse

Bibliografiske detaljer
Hovedforfatter:	Balathasan, L
Andre forfattere:	Muschel, R
Format:	Thesis
Sprog:	English
Udgivet:	2012
Fag:	Tumour pathology Biology (medical sciences) Immunology Tumours Medical Sciences Oncology

Lignende værker

The role of ATF4 in hypoxia-induced cell death in cancer
af: Pike, L, et al.
Udgivet: (2011)

Investigating a role of ASPP2 in the cellular response to infection
af: Lim, Y, et al.
Udgivet: (2014)

Modulating the immune system by amino acid depletion - IDO and beyond
af: Vallius, L
Udgivet: (2011)

The role of host microenvironment in the pathogenesis of multiple myeloma
af: Lwin, STS
Udgivet: (2014)

The role of DLL4-NOTCH signalling in endothelial cell metabolism
af: Harjes, U
Udgivet: (2014)

Mitochondrial modulators of hypoxia-related pathways in tumours
af: Snell, CE
Udgivet: (2013)

Hypoxia-inducible factor is expressed in giant cell tumour of bone and mediates paracrine effects of hypoxia on monocyte-osteoclast differentiation via induction of VEGF
af: Knowles, H, et al.
Udgivet: (2008)

Heterogeneity of tumour response to hypoxia: carbonic anhydrase IX induction defines a subpopulation of hypoxic cells with stem cell properties and drug resistance
af: Ledaki, I
Udgivet: (2013)

Selective permeabilisation of the blood-brain barrier at sites of metastasis.
af: Connell, JJ
Udgivet: (2014)

Novel signalling pathways regulating epithelial-mesenchymal transition in bone metastatic prostate cancer
af: Rao, SR
Udgivet: (2014)

Tumour-stroma interaction in pancreatic cancer
af: Lunardi, S
Udgivet: (2013)

Targeting EGFR signalling pathway in triple negative breast cancer
af: Albukhari, A
Udgivet: (2014)

Targeting EGFR signalling pathway in triple negative breast cancer
af: Albukhari, A
Udgivet: (2014)

The role of HER4 in relation to trastuzumab resistance and prognosis in HER2 positive breast cancer
af: Mohd Nafi, SN
Udgivet: (2014)

Investigating the role of iASPP and ASPP2 in human carcinoma
af: Salter, V
Udgivet: (2014)

Functional analysis of cancer/testis antigens in human cancer
af: Pagotto, A
Udgivet: (2013)

Regulation of stemness and differentiation in colorectal cancer
af: Gandhi, S
Udgivet: (2010)

Impact of TMPRSS2-ERG fusion gene on prostate cancer cell response to chemotherapy, radiotherapy and androgen deprivation therapy
af: Ovtcharov, S
Udgivet: (2015)

Development of models and methods to assess the efficacy of anti-cancer drugs targeted to the mitochondria
af: Potter, M
Udgivet: (2014)

Investigation of the role of ASPP2 in tumourigenesis
af: Tordella, L
Udgivet: (2012)

The role of p53 in hypoxia-induced apoptosis
af: Poole, R
Udgivet: (2010)

The identification and validation of Auger electron-emitting radiopharmaceuticals targeting telomerase for cancer therapy
af: Jackson, M
Udgivet: (2013)

Combining regulatory angiogenic gene therapy and virotherapy for the treatment of breast cancer
af: Bazan Peregrino, M
Udgivet: (2007)

Targeting cell adhesion as a method of sensitising metastatic tumour cells to TRAIL-induced apoptosis
af: Phipps, L
Udgivet: (2011)

The role of astrocytes in brain metastasis
af: O'Brien, E
Udgivet: (2014)

MRI and histological analysis of brain metastasis and the effect of systemic inflammation
af: Hamilton, AMA
Udgivet: (2013)

The structural basis of immune receptor signalling
af: Hamer, R, et al.
Udgivet: (2008)

Role of Notch ligands in tumour angiogenesis
af: Oon, C
Udgivet: (2011)

The role of nitric oxide as a hypoxic cell radiosensitizer
af: Folkes, L
Udgivet: (2013)

Improving intraperitoneal adenovirus virotherapy for ovarian cancer
af: Thoma, CMM
Udgivet: (2011)

Selective targeting of homologous recombination deficiency
af: Zimmer, J
Udgivet: (2014)

The three methyls: the function and therapeutic potential of histone H3K36 trimethylation
af: Pfister, SX
Udgivet: (2014)

CEA-targeted monoclonal antibody therapy in colorectal cancer
af: Conaghan, P, et al.
Udgivet: (2009)

Exploiting pre-existing viral immunity for B cell vaccination against endogenous antigens
af: Wong, S
Udgivet: (2013)

Angiogenesis in human lung tumours
af: Ferguson, ML
Udgivet: (2008)

MiR-215 regulates differentiation in colorectal cancer stem cells
af: Jones, M
Udgivet: (2014)

Autophagy in hematopoiesis and acute myeloid leukemia
af: Watson, A
Udgivet: (2014)

The use of novel xenografting methods to reveal differential gene expression between breast cancer at primary and metastatic sites
af: de Sousa, E, et al.
Udgivet: (2012)

HR23B, a biomarker for HDAC inhibitors
af: Khan, OA
Udgivet: (2013)

Development of sindbis virus as an oncolytic agent
af: Kueberuwa, GLB
Udgivet: (2012)