Characterising the role of circulating immune cells in brain metastasis

Characterising the role of circulating immune cells in brain metastasis

<p>Brain metastasis is a frequent occurrence in cancer patients and carries a high mortality rate. The incidence of brain metastasis is on the rise, highlighting the need for improved therapeutic intervention. Immune cells have been shown to promote disseminated tumour cells to colonise the l...

Cur síos iomlán

Sonraí bibleagrafaíochta
Príomhchruthaitheoir:	Balathasan, L
Rannpháirtithe:	Muschel, R
Formáid:	Tráchtas
Teanga:	English
Foilsithe / Cruthaithe:	2012
Ábhair:	Tumour pathology Biology (medical sciences) Immunology Tumours Medical Sciences Oncology

Míreanna comhchosúla

The role of ATF4 in hypoxia-induced cell death in cancer
de réir: Pike, L, et al.
Foilsithe / Cruthaithe: (2011)

Investigating a role of ASPP2 in the cellular response to infection
de réir: Lim, Y, et al.
Foilsithe / Cruthaithe: (2014)

Modulating the immune system by amino acid depletion - IDO and beyond
de réir: Vallius, L
Foilsithe / Cruthaithe: (2011)

The role of host microenvironment in the pathogenesis of multiple myeloma
de réir: Lwin, STS
Foilsithe / Cruthaithe: (2014)

The role of DLL4-NOTCH signalling in endothelial cell metabolism
de réir: Harjes, U
Foilsithe / Cruthaithe: (2014)

Mitochondrial modulators of hypoxia-related pathways in tumours
de réir: Snell, CE
Foilsithe / Cruthaithe: (2013)

Hypoxia-inducible factor is expressed in giant cell tumour of bone and mediates paracrine effects of hypoxia on monocyte-osteoclast differentiation via induction of VEGF
de réir: Knowles, H, et al.
Foilsithe / Cruthaithe: (2008)

Heterogeneity of tumour response to hypoxia: carbonic anhydrase IX induction defines a subpopulation of hypoxic cells with stem cell properties and drug resistance
de réir: Ledaki, I
Foilsithe / Cruthaithe: (2013)

Selective permeabilisation of the blood-brain barrier at sites of metastasis.
de réir: Connell, JJ
Foilsithe / Cruthaithe: (2014)

Novel signalling pathways regulating epithelial-mesenchymal transition in bone metastatic prostate cancer
de réir: Rao, SR
Foilsithe / Cruthaithe: (2014)

Tumour-stroma interaction in pancreatic cancer
de réir: Lunardi, S
Foilsithe / Cruthaithe: (2013)

Targeting EGFR signalling pathway in triple negative breast cancer
de réir: Albukhari, A
Foilsithe / Cruthaithe: (2014)

Targeting EGFR signalling pathway in triple negative breast cancer
de réir: Albukhari, A
Foilsithe / Cruthaithe: (2014)

The role of HER4 in relation to trastuzumab resistance and prognosis in HER2 positive breast cancer
de réir: Mohd Nafi, SN
Foilsithe / Cruthaithe: (2014)

Investigating the role of iASPP and ASPP2 in human carcinoma
de réir: Salter, V
Foilsithe / Cruthaithe: (2014)

Functional analysis of cancer/testis antigens in human cancer
de réir: Pagotto, A
Foilsithe / Cruthaithe: (2013)

Regulation of stemness and differentiation in colorectal cancer
de réir: Gandhi, S
Foilsithe / Cruthaithe: (2010)

Impact of TMPRSS2-ERG fusion gene on prostate cancer cell response to chemotherapy, radiotherapy and androgen deprivation therapy
de réir: Ovtcharov, S
Foilsithe / Cruthaithe: (2015)

Development of models and methods to assess the efficacy of anti-cancer drugs targeted to the mitochondria
de réir: Potter, M
Foilsithe / Cruthaithe: (2014)

Investigation of the role of ASPP2 in tumourigenesis
de réir: Tordella, L
Foilsithe / Cruthaithe: (2012)

The role of p53 in hypoxia-induced apoptosis
de réir: Poole, R
Foilsithe / Cruthaithe: (2010)

The identification and validation of Auger electron-emitting radiopharmaceuticals targeting telomerase for cancer therapy
de réir: Jackson, M
Foilsithe / Cruthaithe: (2013)

Combining regulatory angiogenic gene therapy and virotherapy for the treatment of breast cancer
de réir: Bazan Peregrino, M
Foilsithe / Cruthaithe: (2007)

Targeting cell adhesion as a method of sensitising metastatic tumour cells to TRAIL-induced apoptosis
de réir: Phipps, L
Foilsithe / Cruthaithe: (2011)

The role of astrocytes in brain metastasis
de réir: O'Brien, E
Foilsithe / Cruthaithe: (2014)

MRI and histological analysis of brain metastasis and the effect of systemic inflammation
de réir: Hamilton, AMA
Foilsithe / Cruthaithe: (2013)

The structural basis of immune receptor signalling
de réir: Hamer, R, et al.
Foilsithe / Cruthaithe: (2008)

Role of Notch ligands in tumour angiogenesis
de réir: Oon, C
Foilsithe / Cruthaithe: (2011)

The role of nitric oxide as a hypoxic cell radiosensitizer
de réir: Folkes, L
Foilsithe / Cruthaithe: (2013)

Improving intraperitoneal adenovirus virotherapy for ovarian cancer
de réir: Thoma, CMM
Foilsithe / Cruthaithe: (2011)

Selective targeting of homologous recombination deficiency
de réir: Zimmer, J
Foilsithe / Cruthaithe: (2014)

The three methyls: the function and therapeutic potential of histone H3K36 trimethylation
de réir: Pfister, SX
Foilsithe / Cruthaithe: (2014)

CEA-targeted monoclonal antibody therapy in colorectal cancer
de réir: Conaghan, P, et al.
Foilsithe / Cruthaithe: (2009)

Exploiting pre-existing viral immunity for B cell vaccination against endogenous antigens
de réir: Wong, S
Foilsithe / Cruthaithe: (2013)

Angiogenesis in human lung tumours
de réir: Ferguson, ML
Foilsithe / Cruthaithe: (2008)

MiR-215 regulates differentiation in colorectal cancer stem cells
de réir: Jones, M
Foilsithe / Cruthaithe: (2014)

Autophagy in hematopoiesis and acute myeloid leukemia
de réir: Watson, A
Foilsithe / Cruthaithe: (2014)

The use of novel xenografting methods to reveal differential gene expression between breast cancer at primary and metastatic sites
de réir: de Sousa, E, et al.
Foilsithe / Cruthaithe: (2012)

HR23B, a biomarker for HDAC inhibitors
de réir: Khan, OA
Foilsithe / Cruthaithe: (2013)

Development of sindbis virus as an oncolytic agent
de réir: Kueberuwa, GLB
Foilsithe / Cruthaithe: (2012)