Gr-1+CD11b+ myeloid-derived suppressor cells: formidable partners in tumor metastasis.
The growth and metastasis of solid tumors not only depends on their ability to escape from immune surveillance but also hinges on their ability to invade the vasculature system as well as to induce the formation of new blood vessels. Gr-1(+)CD11b(+) myeloid-derived suppressor cells (MDSCs), overprod...
| Main Authors: | , , |
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| Format: | Journal article |
| Language: | English |
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2010
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| _version_ | 1797101063684227072 |
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| author | Yang, L Edwards, C Mundy, G |
| author_facet | Yang, L Edwards, C Mundy, G |
| author_sort | Yang, L |
| collection | OXFORD |
| description | The growth and metastasis of solid tumors not only depends on their ability to escape from immune surveillance but also hinges on their ability to invade the vasculature system as well as to induce the formation of new blood vessels. Gr-1(+)CD11b(+) myeloid-derived suppressor cells (MDSCs), overproduced in tumor-bearing hosts, contribute significantly to all these aspects. They also have a potential role in the osteolysis associated with bone metastases. They are formidable partners in tumor metastasis. |
| first_indexed | 2024-03-07T05:46:36Z |
| format | Journal article |
| id | oxford-uuid:e76e0df5-e44c-4142-ac4a-54c8a90de49e |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-07T05:46:36Z |
| publishDate | 2010 |
| record_format | dspace |
| spelling | oxford-uuid:e76e0df5-e44c-4142-ac4a-54c8a90de49e2022-03-27T10:38:36ZGr-1+CD11b+ myeloid-derived suppressor cells: formidable partners in tumor metastasis.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:e76e0df5-e44c-4142-ac4a-54c8a90de49eEnglishSymplectic Elements at Oxford2010Yang, LEdwards, CMundy, GThe growth and metastasis of solid tumors not only depends on their ability to escape from immune surveillance but also hinges on their ability to invade the vasculature system as well as to induce the formation of new blood vessels. Gr-1(+)CD11b(+) myeloid-derived suppressor cells (MDSCs), overproduced in tumor-bearing hosts, contribute significantly to all these aspects. They also have a potential role in the osteolysis associated with bone metastases. They are formidable partners in tumor metastasis. |
| spellingShingle | Yang, L Edwards, C Mundy, G Gr-1+CD11b+ myeloid-derived suppressor cells: formidable partners in tumor metastasis. |
| title | Gr-1+CD11b+ myeloid-derived suppressor cells: formidable partners in tumor metastasis. |
| title_full | Gr-1+CD11b+ myeloid-derived suppressor cells: formidable partners in tumor metastasis. |
| title_fullStr | Gr-1+CD11b+ myeloid-derived suppressor cells: formidable partners in tumor metastasis. |
| title_full_unstemmed | Gr-1+CD11b+ myeloid-derived suppressor cells: formidable partners in tumor metastasis. |
| title_short | Gr-1+CD11b+ myeloid-derived suppressor cells: formidable partners in tumor metastasis. |
| title_sort | gr 1 cd11b myeloid derived suppressor cells formidable partners in tumor metastasis |
| work_keys_str_mv | AT yangl gr1cd11bmyeloidderivedsuppressorcellsformidablepartnersintumormetastasis AT edwardsc gr1cd11bmyeloidderivedsuppressorcellsformidablepartnersintumormetastasis AT mundyg gr1cd11bmyeloidderivedsuppressorcellsformidablepartnersintumormetastasis |