Oxygenation-sensitive cardiovascular magnetic resonance.
Oxygenation-sensitive cardiovascular magnetic resonance (CMR) is a non-contrast technique that allows the non-invasive assessment of myocardial oxygenation. It capitalizes on the fact that deoxygenated hemoglobin in blood can act as an intrinsic contrast agent, changing proton signals in a fashion t...
| Main Authors: | , |
|---|---|
| Format: | Journal article |
| Language: | English |
| Published: |
2013
|
| _version_ | 1826302383430303744 |
|---|---|
| author | Friedrich, MG Karamitsos, T |
| author_facet | Friedrich, MG Karamitsos, T |
| author_sort | Friedrich, MG |
| collection | OXFORD |
| description | Oxygenation-sensitive cardiovascular magnetic resonance (CMR) is a non-contrast technique that allows the non-invasive assessment of myocardial oxygenation. It capitalizes on the fact that deoxygenated hemoglobin in blood can act as an intrinsic contrast agent, changing proton signals in a fashion that can be imaged to reflect the level of blood oxygenation. Increases in O(2) saturation increase the BOLD imaging signal (T2 or T2*), whereas decreases diminish it. This review presents the basic concepts and limitations of the BOLD technique, and summarizes the preclinical and clinical studies in the assessment of myocardial oxygenation with a focus on recent advances. Finally, it provides future directions and a brief look at emerging techniques of this evolving CMR field. |
| first_indexed | 2024-03-07T05:46:44Z |
| format | Journal article |
| id | oxford-uuid:e7767e5c-0cf5-4813-a07e-e79275d03469 |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-07T05:46:44Z |
| publishDate | 2013 |
| record_format | dspace |
| spelling | oxford-uuid:e7767e5c-0cf5-4813-a07e-e79275d034692022-03-27T10:38:55ZOxygenation-sensitive cardiovascular magnetic resonance.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:e7767e5c-0cf5-4813-a07e-e79275d03469EnglishSymplectic Elements at Oxford2013Friedrich, MGKaramitsos, TOxygenation-sensitive cardiovascular magnetic resonance (CMR) is a non-contrast technique that allows the non-invasive assessment of myocardial oxygenation. It capitalizes on the fact that deoxygenated hemoglobin in blood can act as an intrinsic contrast agent, changing proton signals in a fashion that can be imaged to reflect the level of blood oxygenation. Increases in O(2) saturation increase the BOLD imaging signal (T2 or T2*), whereas decreases diminish it. This review presents the basic concepts and limitations of the BOLD technique, and summarizes the preclinical and clinical studies in the assessment of myocardial oxygenation with a focus on recent advances. Finally, it provides future directions and a brief look at emerging techniques of this evolving CMR field. |
| spellingShingle | Friedrich, MG Karamitsos, T Oxygenation-sensitive cardiovascular magnetic resonance. |
| title | Oxygenation-sensitive cardiovascular magnetic resonance. |
| title_full | Oxygenation-sensitive cardiovascular magnetic resonance. |
| title_fullStr | Oxygenation-sensitive cardiovascular magnetic resonance. |
| title_full_unstemmed | Oxygenation-sensitive cardiovascular magnetic resonance. |
| title_short | Oxygenation-sensitive cardiovascular magnetic resonance. |
| title_sort | oxygenation sensitive cardiovascular magnetic resonance |
| work_keys_str_mv | AT friedrichmg oxygenationsensitivecardiovascularmagneticresonance AT karamitsost oxygenationsensitivecardiovascularmagneticresonance |