Synthesis of (+)-obtusenyne.

An enantioselective synthesis of the halogenated medium-ring ether natural product (+)-obtusenyne is reported which uses the ring expansion of a seven-membered ketene acetal by means of a Claisen rearrangement to construct the core nine-membered oxygen heterocycle. The trans substituents across the...

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Những tác giả chính: Mak, S, Curtis, N, Payne, A, Congreve, MS, Wildsmith, A, Francis, C, Davies, J, Pascu, S, Burton, J, Holmes, AB
Định dạng: Journal article
Ngôn ngữ:English
Được phát hành: 2008