The effect of current Schistosoma mansoni infection on the immunogenicity of a candidate TB vaccine, MVA85A, in BCG-vaccinated adolescents: An open-label trial

The effect of current Schistosoma mansoni infection on the immunogenicity of a candidate TB vaccine, MVA85A, in BCG-vaccinated adolescents: An open-label trial

Introduction <br/> Helminth infection may affect vaccine immunogenicity and efficacy. Adolescents, a target population for tuberculosis booster vaccines, often have a high helminth burden. We investigated effects of Schistosoma mansoni (Sm) on the immunogenicity and safety of MVA85A, a model c...

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Detalles Bibliográficos
Autores principales: Wajja, A, Kizito, D, Nassanga, B, Nalwoga, A, Kabagenyi, J, Kimuda, S, Galiwango, R, Mutonyi, G, Vermaak, S, Satti, I, Verweij, J, Tukahebwa, E, Cose, S, Levin, J, Kaleebu, P, Elliott, A, McShane, H
Otros Autores: Diemert, D
Formato: Journal article
Lenguaje:English
Publicado: Public Library of Science 2017

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