DNA interstrand crosslink repair during G1 involves nucleotide excision repair and DNA polymerase zeta.

The repair mechanisms acting on DNA interstrand crosslinks (ICLs) in eukaryotes are poorly understood. Here, we provide evidence for a pathway of ICL processing that uses components from both nucleotide excision repair (NER) and translesion synthesis (TLS) and predominates during the G1 phase of the...

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Main Authors: Sarkar, S, Davies, A, Ulrich, H, McHugh, P
格式: Journal article
语言:English
出版: 2006